PDB entry 2ei8

View 2ei8 on RCSB PDB site
Description: FACTOR XA IN COMPLEX WITH THE INHIBITOR (1S,2R,4S)-N1-[(5-chloroindol-2-yl)carbonyl]-4-(N,N-dimethylcarbamoyl)-N2-[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]-1,2-cyclohexanediamine
Class: hydrolase
Keywords: glycoprotein, hydrolase, serine protease, plasma, blood coagulation factor, protein inhibitor complex, calcium-binding
Deposited on 2007-03-12, released 2008-03-18
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.208
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: coagulation factor x, heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d2ei8a_
  • Chain 'B':
    Compound: coagulation factor x, light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d2ei8b_
  • Heterogens: CA, DT8, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2ei8A (A:)
    ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
    qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
    tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
    cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmk
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2ei8B (B:)
    trklcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtle