PDB entry 2eg8

View 2eg8 on RCSB PDB site
Description: The crystal structure of E. coli dihydroorotase complexed with 5-fluoroorotic acid
Class: hydrolase
Keywords: amidohydrolase, TIM barrel
Deposited on 2007-02-28, released 2007-07-03
The last revision prior to the SCOP 1.75 freeze date was dated 2007-07-03, with a file datestamp of 2007-06-29.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.174
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydroorotase
    Species: Escherichia coli
    Gene: PYRC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05020
      • modified residue (101)
      • conflict (118)
    Domains in SCOP 1.75: d2eg8a1
  • Chain 'B':
    Compound: dihydroorotase
    Species: Escherichia coli
    Gene: PYRC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05020
      • modified residue (101)
      • conflict (118)
    Domains in SCOP 1.75: d2eg8b1
  • Heterogens: ZN, FOT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2eg8A (A:)
tapsqvlkirrpddwhlhlrdgdmlktvvpytseiygraivmpnlappvttveaavayrq
rildavpaghdftplmtcyltdsldpnelergfnegvftaaklypanattnsshgvtsvd
aimpvlermekigmpllvhgevthadidifdrearfiesvmeplrqrltalkvvfehitt
kdaadyvrdgnerlaatitpqhlmfnrnhmlvggvrphlyclpilkrnihqqalrelvas
gfnrvflgtdsapharhrkesscgcagcfnaptalgsyatvfeemnalqhfeafcsvngp
qfyglpvndtfielvreeqqvaesialtddtlvpflagetvrwsvkq

    Sequence, based on observed residues (ATOM records): (download) 
    >2eg8A (A:)
sqvlkirrpddwhlhlrdgdmlktvvpytseiygraivmpnlappvttveaavayrqril
davpaghdftplmtcyltdsldpnelergfnegvftaaklypanattnsshgvtsvdaim
pvlermekigmpllvhgevthadidifdrearfiesvmeplrqrltalkvvfehittkda
adyvrdgnerlaatitpqhlmfnrnhmlvggvrphlyclpilkrnihqqalrelvasgfn
rvflgtdsapharhrkesscgcagcfnaptalgsyatvfeemnalqhfeafcsvngpqfy
glpvndtfielvreeqqvaesialtddtlvpflagetvrwsvk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2eg8B (B:)
tapsqvlkirrpddwhlhlrdgdmlktvvpytseiygraivmpnlappvttveaavayrq
rildavpaghdftplmtcyltdsldpnelergfnegvftaaklypanattnsshgvtsvd
aimpvlermekigmpllvhgevthadidifdrearfiesvmeplrqrltalkvvfehitt
kdaadyvrdgnerlaatitpqhlmfnrnhmlvggvrphlyclpilkrnihqqalrelvas
gfnrvflgtdsapharhrkesscgcagcfnaptalgsyatvfeemnalqhfeafcsvngp
qfyglpvndtfielvreeqqvaesialtddtlvpflagetvrwsvkq

    Sequence, based on observed residues (ATOM records): (download) 
    >2eg8B (B:)
sqvlkirrpddwhlhlrdgdmlktvvpytseiygraivmpnlappvttveaavayrqril
davpaghdftplmtcyltdsldpnelergfnegvftaaklypangvtsvdaimpvlerme
kigmpllvhgevthadidifdrearfiesvmeplrqrltalkvvfehittkdaadyvrdg
nerlaatitpqhlmfnrnhmlvggvrphlyclpilkrnihqqalrelvasgfnrvflgtd
sapharhrkesscgcagcfnaptalgsyatvfeemnalqhfeafcsvngpqfyglpvndt
fielvreeqqvaesialtddtlvpflagetvrwsvk