PDB entry 2e9x

View 2e9x on RCSB PDB site
Description: The crystal structure of human GINS core complex
Class: replication
Keywords: GINS complex, Eukaryotic DNA replication, REPLICATION
Deposited on 2007-01-27, released 2007-04-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA replication complex GINS protein PSF1
    Species: Homo sapiens [TaxId:9606]
    Gene: Psf1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2e9xa1
  • Chain 'B':
    Compound: DNA replication complex GINS protein PSF2
    Species: Homo sapiens [TaxId:9606]
    Gene: PSF2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2e9xb1, d2e9xb2
  • Chain 'C':
    Compound: GINS complex subunit 3
    Species: Homo sapiens [TaxId:9606]
    Gene: Psf3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9BRX5
      • cloning artifact (0-2)
    Domains in SCOPe 2.08: d2e9xc1, d2e9xc2, d2e9xc3
  • Chain 'D':
    Compound: GINS complex subunit 4
    Species: Homo sapiens [TaxId:9606]
    Gene: sld5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2e9xd1, d2e9xd2
  • Chain 'E':
    Compound: DNA replication complex GINS protein PSF1
    Species: Homo sapiens [TaxId:9606]
    Gene: Psf1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2e9xe_
  • Chain 'F':
    Compound: DNA replication complex GINS protein PSF2
    Species: Homo sapiens [TaxId:9606]
    Gene: PSF2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2e9xf1, d2e9xf2
  • Chain 'G':
    Compound: GINS complex subunit 3
    Species: Homo sapiens [TaxId:9606]
    Gene: Psf3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2e9xg1, d2e9xg2
  • Chain 'H':
    Compound: GINS complex subunit 4
    Species: Homo sapiens [TaxId:9606]
    Gene: sld5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2e9xh1, d2e9xh2
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2e9xA (A:)
mfcekamelirelhrapegqlpafnedglrqvleemkalyeqnqsdvneaksggrsdlip
tikfrhcsllrnrrctvaylydrllriralrweygsvlpnalrfhmaaeemewfnnykrs
latymrslggdeglditqdmkppkslyie

    Sequence, based on observed residues (ATOM records): (download) 
    >2e9xA (A:)
mfcekamelirelhrapegqlpafnedglrqvleemkalyeqnqsdvneaksggrsdlip
tikfrhcsllrnrrctvaylydrllriralrweygsvlpnalrfhmaaeemewfnnykrs
latymrslggdeglditqdmkppk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2e9xB (B:)
mdaaeveflaekelvtiipnfsldkiyliggdlgpfnpglpvevplwlainlkqrqkcrl
lppewmdveklekmrdherkeetftpmpspyymeltklllnhasdnipkadeirtlvkdm
wdtriaklrvsadsfvrqqeahakldnltlmeintsgtfltqalnhmyklrtnlqplest
qsqdf

    Sequence, based on observed residues (ATOM records): (download) 
    >2e9xB (B:)
mdaaeveflaekelvtiipnfsldkiyliggdlgpfnpglpvevplwlainlkqrqkcrl
lppewmdveklekmrdherkeetftpmpspyymeltklllnhasdnipkadeirtlvkdm
wdtriaklrvsadsfvrqqeahakldnltlmeintsgtfltqalnhmyklrtnlq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2e9xC (C:)
gphmseayfrvesgalgpeenflslddilmsheklpvrtetamprlgafflersagaetd
navpqgsklelplwlakglfdnkrrilsvelpkiyqegwrtvfsadpnvvdlhkmgphfy
gfgsqllhfdspenadisqsllqtfigrfrrimdssqnaynedtsalvarldemerglfq
tgqkglndfqcwekgqasqitasnlvqnykkrkftdmed

    Sequence, based on observed residues (ATOM records): (download) 
    >2e9xC (C:)
gphmseayfrvesgalgpeenflslddilmsheklpvrtetamprlgaffdnavpqgskl
elplwlakglfdnkrrilsvelpkiyqegwrtvfsadpnvvdlhkmgphfygfgsqllhf
dspenadisqsllqtfigrfrrimdssqnaynedtsalvarldemerglfqtgqkglndf
qcwekg

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2e9xD (D:)
mteevdflgqdsdggseevvltpaelierleqawmnekfapelleskpeivecvmeqleh
meenlrrakredlkvsihqmemeriryvlssylrcrlmkiekffphvlekektrpegeps
slspeelafarefmantesylknvalkhmppnlqkvdlfravpkpdldsyvflrvrerqe
nilvepdtdeqrdyvidlekgsqhliryktiaplvasgavqli

    Sequence, based on observed residues (ATOM records): (download) 
    >2e9xD (D:)
ltpaelierleqawmnekfapelleskpeivecvmeqlehmeenedlkvsihqmemerir
yvlssylrcrlmkiekffphvlekektrpegepsslspeelafarefmantesylknval
khmppnlqkvdlfravpkpdldsyvflrvrerqenilvepdtdeqrdyvidlekgsqhli
ryktiaplvasgavqli

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2e9xE (E:)
mfcekamelirelhrapegqlpafnedglrqvleemkalyeqnqsdvneaksggrsdlip
tikfrhcsllrnrrctvaylydrllriralrweygsvlpnalrfhmaaeemewfnnykrs
latymrslggdeglditqdmkppkslyie

    Sequence, based on observed residues (ATOM records): (download) 
    >2e9xE (E:)
mfcekamelirelhrapegqlpafnedglrqvleemkalyeqnqsdvneaksggrsdlip
tikfrhcsllrnrrctvaylydrllriralrweygsvlpnalrfhmaaeemewfnnykrs
latymrslggdeglditqdmkppk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2e9xF (F:)
mdaaeveflaekelvtiipnfsldkiyliggdlgpfnpglpvevplwlainlkqrqkcrl
lppewmdveklekmrdherkeetftpmpspyymeltklllnhasdnipkadeirtlvkdm
wdtriaklrvsadsfvrqqeahakldnltlmeintsgtfltqalnhmyklrtnlqplest
qsqdf

    Sequence, based on observed residues (ATOM records): (download) 
    >2e9xF (F:)
mdaaeveflaekelvtiipnfsldkiyliggdlgpfnpglpvevplwlainlkqrqkcrl
lppewmdveklekmrdherkeetftpmpspyymeltklllnhasdnipkadeirtlvkdm
wdtriaklrvsadsfvrqqeahakldnltlmeintsgtfltqalnhmyklrtnlq

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2e9xG (G:)
gphmseayfrvesgalgpeenflslddilmsheklpvrtetamprlgafflersagaetd
navpqgsklelplwlakglfdnkrrilsvelpkiyqegwrtvfsadpnvvdlhkmgphfy
gfgsqllhfdspenadisqsllqtfigrfrrimdssqnaynedtsalvarldemerglfq
tgqkglndfqcwekgqasqitasnlvqnykkrkftdmed

    Sequence, based on observed residues (ATOM records): (download) 
    >2e9xG (G:)
mseayfrvesgalgpeenflslddilmsheklpvrtetamprlgaffdnavpqgsklelp
lwlakglfdnkrrilsvelpkiyqegwrtvfsadpnvvdlhkmgphfygfgsqllhfdsp
enadisqsllqtfigrfrrimdssqnaynedtsalvarldemerglfqtgqkglndfqcw
ekg

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2e9xH (H:)
mteevdflgqdsdggseevvltpaelierleqawmnekfapelleskpeivecvmeqleh
meenlrrakredlkvsihqmemeriryvlssylrcrlmkiekffphvlekektrpegeps
slspeelafarefmantesylknvalkhmppnlqkvdlfravpkpdldsyvflrvrerqe
nilvepdtdeqrdyvidlekgsqhliryktiaplvasgavqli

    Sequence, based on observed residues (ATOM records): (download) 
    >2e9xH (H:)
ltpaelierleqawmnekfapelleskpeivecvmeqlehmeenedlkvsihqmemerir
yvlssylrcrlmkiekffphvlekektrpegepsslspeelafarefmantesylknval
khmppnlqkvdlfravpkpdldsyvflrvrerqenilvepdtdeqrdyvidlekgsqhli
ryktiaplvasgavqli