PDB entry 2e42

View 2e42 on RCSB PDB site
Description: Crystal structure of C/EBPbeta Bzip homodimer V285A mutant bound to A High Affinity DNA fragment
Class: transcription/DNA
Keywords: protein-DNA complex, transcription/DNA
Deposited on 2006-12-01, released 2007-12-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.232
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: CCAAT/enhancer-binding protein beta
  Species: Homo sapiens [TaxId:9606]
  Gene: CEBPB, TCF5
  Database cross-references and differences (RAF-indexed):
  • Uniprot P17676
    • engineered (26)
  Domains in SCOPe 2.08: d2e42a_
• Chain 'B':
  Compound: CCAAT/enhancer-binding protein beta
  Species: Homo sapiens [TaxId:9606]
  Gene: CEBPB, TCF5
  Database cross-references and differences (RAF-indexed):
  • Uniprot P17676
    • engineered (26)
  Domains in SCOPe 2.08: d2e42b_
• Chain 'C':
  Compound: DNA (5'-d(p*dtp*dap*dgp*dgp*dap*dtp*dtp*dgp*dcp*dgp*dcp*dap*dap*dtp*dap*dt)-3')
  
• Chain 'D':
  Compound: DNA (5'-d(p*dap*dap*dtp*dap*dtp*dtp*dgp*dcp*dgp*dcp*dap*dap*dtp*dcp*dcp*dt)-3')
  
• Heterogens: HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence, based on SEQRES records: (download)
  

  >2e42A (A:)
  vkskakktvdkhsdeykirrernniaarksrdkakmrnletqhkvleltaenerlqkkve
  qlsrelstlrnlfkqlpe
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >2e42A (A:)
  dkhsdeykirrernniaarksrdkakmrnletqhkvleltaenerlqkkveqlsrelstl
  rnlfk
  

  
  
• Chain 'B':
  Sequence, based on SEQRES records: (download)
  

  >2e42B (B:)
  vkskakktvdkhsdeykirrernniaarksrdkakmrnletqhkvleltaenerlqkkve
  qlsrelstlrnlfkqlpe
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >2e42B (B:)
  dkhsdeykirrernniaarksrdkakmrnletqhkvleltaenerlqkkveqlsrelstl
  rnlfkql
  

  
  
• Chain 'C':
  No sequence available.
  
  
• Chain 'D':
  No sequence available.