PDB entry 2e41
View 2e41 on RCSB PDB site
Description: Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii Complexed with the Reaction Product Analog Biotinol-5'-AMP, Mutations R48A and K111A
Class: ligase
Keywords: Biotin Biosynthesis, Dimer, Structural Genomics, NPPSFA, National Project on Protein Structural and Functional Analyses, RIKEN Structural Genomics/Proteomics Initiative, RSGI, LIGASE
Deposited on
2006-12-01, released
2007-06-05
The last revision prior to the SCOPe 2.08 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-08.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.183
AEROSPACI score: 0.54
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: biotin--[acetyl-CoA-carboxylase] ligase
Species: Pyrococcus horikoshii [TaxId:70601]
Gene: bpl
Database cross-references and differences (RAF-indexed):
- Uniprot O57883 (0-234)
- engineered (47)
- engineered (110)
Domains in SCOPe 2.08: d2e41a1, d2e41a2 - Chain 'B':
Compound: biotin--[acetyl-CoA-carboxylase] ligase
Species: Pyrococcus horikoshii [TaxId:70601]
Gene: bpl
Database cross-references and differences (RAF-indexed):
- Uniprot O57883 (0-End)
- engineered (47)
- engineered (110)
Domains in SCOPe 2.08: d2e41b1, d2e41b2 - Heterogens: BTX, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>2e41A (A:)
mlglktsiigrrviyfqeitstnefaktsyleegtvivadkqtmghgalnrkwespeggl
wlsivlspkvpqkdlpkivflgavgvvetlkefsidgrikwpndvlvnykaiagvlvegk
gdkivlgiglnvnnkvpngatsmklelgsevpllsvfrslitnldrlylnflknpmdiln
lvrdnmilgvrvkilgdgsfegiaediddfgrliirldsgevkkviygdvslrfl
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2e41B (B:)
mlglktsiigrrviyfqeitstnefaktsyleegtvivadkqtmghgalnrkwespeggl
wlsivlspkvpqkdlpkivflgavgvvetlkefsidgrikwpndvlvnykaiagvlvegk
gdkivlgiglnvnnkvpngatsmklelgsevpllsvfrslitnldrlylnflknpmdiln
lvrdnmilgvrvkilgdgsfegiaediddfgrliirldsgevkkviygdvslrfl
Sequence, based on observed residues (ATOM records): (download)
>2e41B (B:)
mlglktsiigrrviyfqeitstnefaktsyleegtvivadkqtmghgalnrkwespeggl
wlsivlspkvpqkdlpkivflgavgvvetlkefsidgrikwpndvlvnykaiagvlvegk
gdkivlgiglnvnnkvpngatsmklelgsevpllsvfrslitnldrlylnflknpmdiln
lvrdnmilgvrvkilgdgsfegiaediddfgrliirldsgevkkviygdvsl