PDB entry 2e21

View 2e21 on RCSB PDB site
Description: Crystal structure of TilS in a complex with AMPPNP from Aquifex aeolicus.
Class: ligase
Keywords: Rossmann-fold, Structural Genomics, NPPSFA, National Project on Protein Structural and Functional Analyses, RIKEN Structural Genomics/Proteomics Initiative, RSGI, LIGASE
Deposited on 2006-11-06, released 2007-11-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.222
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tRNA(Ile)-lysidine synthase
    Species: Aquifex aeolicus [TaxId:63363]
    Gene: tilS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2e21a1, d2e21a2
  • Chain 'B':
    Compound: tRNA(Ile)-lysidine synthase
    Species: Aquifex aeolicus [TaxId:63363]
    Gene: tilS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2e21b1, d2e21b2
  • Chain 'C':
    Compound: tRNA(Ile)-lysidine synthase
    Species: Aquifex aeolicus [TaxId:63363]
    Gene: tilS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2e21c1, d2e21c2
  • Chain 'D':
    Compound: tRNA(Ile)-lysidine synthase
    Species: Aquifex aeolicus [TaxId:63363]
    Gene: tilS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2e21d1, d2e21d2
  • Heterogens: ANP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2e21A (A:)
mnpesrvirkvlalqndekifsgerrvliafsggvdsvvltdvllklknyfslkevalah
fnhmlresaerdeefckefakernmkifvgkedvrafakenrmsleeagrflrykflkei
lesegfdciatahhlndlletsllfftrgtgldgligflpkeevirrplyyvkrseieey
akfkglrwvedetnyevsiprnrirhrvipelkrinenledtflkmvkvlraerefleee
aqklykevkkgncldvkklkekplalqrrvirkfigekdyekvelvrsllekggevnlgk
gkvlkrkerwlcfspev

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2e21B (B:)
mnpesrvirkvlalqndekifsgerrvliafsggvdsvvltdvllklknyfslkevalah
fnhmlresaerdeefckefakernmkifvgkedvrafakenrmsleeagrflrykflkei
lesegfdciatahhlndlletsllfftrgtgldgligflpkeevirrplyyvkrseieey
akfkglrwvedetnyevsiprnrirhrvipelkrinenledtflkmvkvlraerefleee
aqklykevkkgncldvkklkekplalqrrvirkfigekdyekvelvrsllekggevnlgk
gkvlkrkerwlcfspev

    Sequence, based on observed residues (ATOM records): (download) 
    >2e21B (B:)
mnpesrvirkvlalqndekifsgerrvliafsggvdsvvltdvllklknyfslkevalah
fnhmlresaerdeefckefakernmkifvgkedvrafakenrmsleeagrflrykflkei
lesegfdciatahhlndlletsllfftrgtgldgligflpkeevirrplyyvkrseieey
akfkglrwvedetnyevsiprnrirhrvipelkrinenledtflkmvkvlraerefleee
aqklykevkkgncldvkklkekplalqrrvirkfigekdyekvelvrsllekggevnlgk
gkvlkrkerwlcfs

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2e21C (C:)
mnpesrvirkvlalqndekifsgerrvliafsggvdsvvltdvllklknyfslkevalah
fnhmlresaerdeefckefakernmkifvgkedvrafakenrmsleeagrflrykflkei
lesegfdciatahhlndlletsllfftrgtgldgligflpkeevirrplyyvkrseieey
akfkglrwvedetnyevsiprnrirhrvipelkrinenledtflkmvkvlraerefleee
aqklykevkkgncldvkklkekplalqrrvirkfigekdyekvelvrsllekggevnlgk
gkvlkrkerwlcfspev

    Sequence, based on observed residues (ATOM records): (download) 
    >2e21C (C:)
mnpesrvirkvlalqndekifsgerrvliafsggvdsvvltdvllklknyfslkevalah
fnhmlresaerdeefckefakernmkifvgkedvrafakenrmsleeagrflrykflkei
lesegfdciatahhlndlletsllfftrgtgldgligflpkeevirrplyyvkrseieey
akfkglrwvedetnyevsiprnrirhrvipelkrinenledtflkmvkvlraerefleee
aqklykevkkgncldvkklkekplalqrrvirkfigekdyekvelvrsllekggevnlgk
gkvlkrkerwlcfs

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2e21D (D:)
mnpesrvirkvlalqndekifsgerrvliafsggvdsvvltdvllklknyfslkevalah
fnhmlresaerdeefckefakernmkifvgkedvrafakenrmsleeagrflrykflkei
lesegfdciatahhlndlletsllfftrgtgldgligflpkeevirrplyyvkrseieey
akfkglrwvedetnyevsiprnrirhrvipelkrinenledtflkmvkvlraerefleee
aqklykevkkgncldvkklkekplalqrrvirkfigekdyekvelvrsllekggevnlgk
gkvlkrkerwlcfspev

    Sequence, based on observed residues (ATOM records): (download) 
    >2e21D (D:)
mnpesrvirkvlalqndekifsgerrvliafsggvdsvvltdvllklknyfslkevalah
fnhmlresaerdeefckefakernmkifvgkedvrafakenrmsleeagrflrykflkei
lesegfdciatahhlndlletsllfftrgtgldgligflpkeevirrplyyvkrseieey
akfkglrwvedetnyevsiprnrirhrvipelkrinenledtflkmvkvlraerefleee
aqklykevkkgncldvkklkekplalqrrvirkfigekdyekvelvrsllekggevnlgk
gkvlkrkerwlcfs