PDB entry 2e14

View 2e14 on RCSB PDB site
Description: The structure of ERK2 in complex with FR148083
Class: transferase
Keywords: Protein Kinase, TRANSFERASE
Deposited on 2006-10-18, released 2007-09-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-02-06, with a file datestamp of 2013-02-01.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.26
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2e14a_
  • Heterogens: FRR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2e14A (A:)
gdlgsdelmaaaaaagagpemvrgqvfdvgprytnlsyigegaygmvcsaydnvnkvrva
ikkispfehqtycqrtlreikillrfrheniigindiiraptieqmkdvyivqdlmetdl
ykllktqhlsndhicyflyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglar
vadpdhdhtgflteyvatrwyrapeimlnskgytksidiwsvgcilaemlsnrpifpgkh
yldqlnhilgilgspsqedlnciinlkarnyllslphknkvpwnrlfpnadskaldlldk
mltfnphkrieveqalahpyleqyydpsdepiaeapfkfdmelddlpkeklkelifeeta
rfqpgyrs

    Sequence, based on observed residues (ATOM records): (download) 
    >2e14A (A:)
pemvrgqvfdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispfehqtycqrtlr
eikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhicyfl
yqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadvatrwyrapeimlns
kgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsqedlnciinlkarn
yllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqalahpyleqyydpsde
piaeapfkfdmelddlpkeklkelifeetarfqpg