PDB entry 2dzw

View 2dzw on RCSB PDB site
Description: Structure of mutant tryptophan synthase alpha-subunit (E244A) from a hyperthermophile, Pyrococcus furiosus
Class: Lyase
Keywords: tryptophan synthase alpha-subunit, hyperthermophile, pyrococcus furiosus, x-ray analysis, stability, calorimetry, Lyase, Structural Genomics, NPPSFA, National Project on Protein Structural and Functional Analyses, RIKEN Structural Genomics/Proteomics Initiative, RSGI
Deposited on 2006-09-30, released 2007-08-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.192
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tryptophan synthase alpha chain
    Species: Pyrococcus furiosus [TaxId:2261]
    Gene: trpA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8U094 (0-247)
      • engineered (243)
    Domains in SCOPe 2.08: d2dzwa_
  • Chain 'B':
    Compound: tryptophan synthase alpha chain
    Species: Pyrococcus furiosus [TaxId:2261]
    Gene: trpA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8U094 (0-247)
      • engineered (243)
    Domains in SCOPe 2.08: d2dzwb_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2dzwA (A:)
mfkdgslipyltagdpdkqstlnfllaldeyagaielgipfsdpiadgktiqeshyralk
ngfklreafwivkefrrhsstpivlmtyynpiyragvrnflaeakasgvdgilvvdlpvf
hakefteiareegiktvflaapntpderlkviddmttgfvylvslygttgareeipktay
dllrrakricrnkvavgfgvskrehvvsllkegangvvvgsalvkiigekgreateflkk
kveallgi

    Sequence, based on observed residues (ATOM records): (download) 
    >2dzwA (A:)
mfkdgslipyltagdpdkqstlnfllaldeyagaielgipfsdpiadgktiqeshyralk
ngfklreafwivkefrrhsstpivlmtyynpiyragvrnflaeakasgvdgilvvdlpvf
hakefteiareegiktvflaapntpderlkviddmttgfvylvslygteeipktaydllr
rakricrnkvavgfgvskrehvvsllkegangvvvgsalvkiigekgreateflkkkvea
llgi

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2dzwB (B:)
mfkdgslipyltagdpdkqstlnfllaldeyagaielgipfsdpiadgktiqeshyralk
ngfklreafwivkefrrhsstpivlmtyynpiyragvrnflaeakasgvdgilvvdlpvf
hakefteiareegiktvflaapntpderlkviddmttgfvylvslygttgareeipktay
dllrrakricrnkvavgfgvskrehvvsllkegangvvvgsalvkiigekgreateflkk
kveallgi

    Sequence, based on observed residues (ATOM records): (download) 
    >2dzwB (B:)
mfkdgslipyltagdpdkqstlnfllaldeyagaielgipfsdpiadgktiqeshyralk
ngfklreafwivkefrrhsstpivlmtyynpiyragvrnflaeakasgvdgilvvdlpvf
hakefteiareegiktvflaapntpderlkviddmttgfvylvslygtteeipktaydll
rrakricrnkvavgfgvskrehvvsllkegangvvvgsalvkiigekgreateflkkkve
allgi