PDB entry 2dyh

View 2dyh on RCSB PDB site
Description: Crystal structure of the Keap1 protein in complexed with the N-terminal region of the Nrf2 transcription factor
Class: transcription
Keywords: bet-propeller, Kelch motif, Structural Genomics, NPPSFA, National Project on Protein Structural and Functional Analyses, RIKEN Structural Genomics/Proteomics Initiative, RSGI, TRANSCRIPTION
Deposited on 2006-09-14, released 2007-09-04
The last revision prior to the SCOP 1.75 freeze date was dated 2008-06-17, with a file datestamp of 2008-06-13.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.174
AEROSPACI score: 0.6 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Kelch-like ECH-associated protein 1
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2dyha1
  • Chain 'B':
    Compound: Nrf2/Neh2 peptide from Nuclear factor erythroid 2-related factor 2
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2dyhA (A:)
mtlhkptqavpcrapkvgrliytaggyfrqslsyleaynpsngswlrladlqvprsglag
cvvggllyavggrnnspdgntdssaldcynpmtnqwspcasmsvprnrigvgvidghiya
vggshgcihhssveryeperdewhlvapmltrrigvgvavlnrllyavggfdgtnrlnsa
ecyypernewrmitpmntirsgagvcvlhnciyaaggydgqdqlnsverydvetetwtfv
apmrhhrsalgitvhqgkiyvlggydghtfldsvecydpdsdtwsevtrmtsgrsgvgva
vtmepcrkqidqqnctcy

    Sequence, based on observed residues (ATOM records): (download) 
    >2dyhA (A:)
vgrliytaggyfrqslsyleaynpsngswlrladlqvprsglagcvvggllyavggrnns
pdgntdssaldcynpmtnqwspcasmsvprnrigvgvidghiyavggshgcihhssvery
eperdewhlvapmltrrigvgvavlnrllyavggfdgtnrlnsaecyypernewrmitpm
ntirsgagvcvlhnciyaaggydgqdqlnsverydvetetwtfvapmrhhrsalgitvhq
gkiyvlggydghtfldsvecydpdsdtwsevtrmtsgrsgvgvavtmepcrkqidq

  • Chain 'B':
    No sequence available.