PDB entry 2dsp
View 2dsp on RCSB PDB site
Description: Structural Basis for the Inhibition of Insulin-like Growth Factors by IGF Binding Proteins
Class: protein binding/hormone/growth factor
Keywords: IGF, IGFBP, Insulin
Deposited on
2006-07-05, released
2006-08-22
The last revision prior to the SCOP 1.75 freeze date was dated
2006-09-12, with a file datestamp of
2007-06-04.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.223
AEROSPACI score: 0.35
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'B':
Compound: Insulin-like growth factor-binding protein 4
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d2dspb1 - Chain 'I':
Compound: Insulin-like growth factor IB
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d2dspi1 - Heterogens: HOH
PDB Chain Sequences:
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2dspB (B:)
deaihcppcseeklarcrppvgceelvrepgcgccatcalglgmpcgvytprcgsglrcy
pprgvekplhtlmhgqgvcmelaeieaiqesl
Sequence, based on observed residues (ATOM records): (download)
>2dspB (B:)
deaihcppcseeklarcrppvgceelvrepgcgccatcalglgmpcgvytprcgsglrcy
ppgvekplhtlmhgqgvcmelaeieaiqesl
- Chain 'I':
Sequence, based on SEQRES records: (download)
>2dspI (I:)
gpetlcgaelvdalqfvcgdrgfyfnkptgygsssrrapqtgivdeccfrscdlrrlemy
caplkpaksa
Sequence, based on observed residues (ATOM records): (download)
>2dspI (I:)
petlcgaelvdalqfvcgdrgfyfnkptqtgivdeccfrscdlrrlemycaplkpak