PDB entry 2doi

View 2doi on RCSB PDB site
Description: The X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcus protein PAM
Class: hydrolase
Keywords: plasminogen, kringle domain, lysine-binding site, pseudo-lysine moiety
Deposited on 2006-04-29, released 2006-12-05
The last revision prior to the SCOP 1.73 freeze date was dated 2006-12-05, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: 0.202
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: angiostatin
    Species: HOMO SAPIENS
    Gene: PLG
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2doia1, d2doia2
  • Chain 'B':
    Compound: Plasminogen-binding group A steptococcal M-like protein PAM
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Plasminogen-binding group A steptococcal M-like protein PAM
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Chain 'X':
    Compound: angiostatin
    Species: HOMO SAPIENS
    Gene: PLG
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2doix1, d2doix2

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2doiA (A:)
lsecktgngknyrgtmsktkngitcqkwsstsphrprfspathpsegleenycrnpdndp
qgpwcyttdpekrydycdileceeecmhcsgenydgkisktmsglecqawdsqsphahgy
ipskfpnknlkknycrnpdrelrpwcfttdpnkrwelcdiprcttpppssgptyqclkgt
genyrgnvavtvsghtcqhwsaqtphthertpenfpcknldenycrnpdgkrap

    Sequence, based on observed residues (ATOM records): (download) 
    >2doiA (A:)
lsecktgngknyrgtmsktkngitcqkwsstsphrprfspathpsegleenycrnpdndp
qgpwcyttdpekrydycdileceeecmhcsgenydgkisktmsglecqawdsqsphahgy
ipskfpnknlkknycrnpdrelrpwcfttdpnkrwelcdiprct

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'X':
    Sequence, based on SEQRES records: (download) 
    >2doiX (X:)
lsecktgngknyrgtmsktkngitcqkwsstsphrprfspathpsegleenycrnpdndp
qgpwcyttdpekrydycdileceeecmhcsgenydgkisktmsglecqawdsqsphahgy
ipskfpnknlkknycrnpdrelrpwcfttdpnkrwelcdiprcttpppssgptyqclkgt
genyrgnvavtvsghtcqhwsaqtphthertpenfpcknldenycrnpdgkrap

    Sequence, based on observed residues (ATOM records): (download) 
    >2doiX (X:)
lsecktgngknyrgtmsktkngitcqkwsstsphrprfspathpsegleenycrnpdndp
qgpwcyttdpekrydycdileceeecmhcsgenydgkisktmsglecqawdsqsphahgy
ipskfpnknlkknycrnpdrelrpwcfttdpnkrwelcdiprcttpck