PDB entry 2doi

View 2doi on RCSB PDB site
Description: The X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcus protein PAM
Class: hydrolase
Keywords: plasminogen, kringle domain, lysine-binding site, pseudo-lysine moiety, HYDROLASE
Deposited on 2006-04-29, released 2006-12-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.09 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: angiostatin
    Species: Homo sapiens [TaxId:9606]
    Gene: PLG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2doia1, d2doia2
  • Chain 'B':
    Compound: Plasminogen-binding group A streptococcal M-like protein PAM
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Plasminogen-binding group A streptococcal M-like protein PAM
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Chain 'X':
    Compound: angiostatin
    Species: Homo sapiens [TaxId:9606]
    Gene: PLG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2doix1, d2doix2

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2doiA (A:)
lsecktgngknyrgtmsktkngitcqkwsstsphrprfspathpsegleenycrnpdndp
qgpwcyttdpekrydycdileceeecmhcsgenydgkisktmsglecqawdsqsphahgy
ipskfpnknlkknycrnpdrelrpwcfttdpnkrwelcdiprcttpppssgptyqclkgt
genyrgnvavtvsghtcqhwsaqtphthertpenfpcknldenycrnpdgkrap

    Sequence, based on observed residues (ATOM records): (download) 
    >2doiA (A:)
lsecktgngknyrgtmsktkngitcqkwsstsphrprfspathpsegleenycrnpdndp
qgpwcyttdpekrydycdileceeecmhcsgenydgkisktmsglecqawdsqsphahgy
ipskfpnknlkknycrnpdrelrpwcfttdpnkrwelcdiprct

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'X':
    Sequence, based on SEQRES records: (download) 
    >2doiX (X:)
lsecktgngknyrgtmsktkngitcqkwsstsphrprfspathpsegleenycrnpdndp
qgpwcyttdpekrydycdileceeecmhcsgenydgkisktmsglecqawdsqsphahgy
ipskfpnknlkknycrnpdrelrpwcfttdpnkrwelcdiprcttpppssgptyqclkgt
genyrgnvavtvsghtcqhwsaqtphthertpenfpcknldenycrnpdgkrap

    Sequence, based on observed residues (ATOM records): (download) 
    >2doiX (X:)
lsecktgngknyrgtmsktkngitcqkwsstsphrprfspathpsegleenycrnpdndp
qgpwcyttdpekrydycdileceeecmhcsgenydgkisktmsglecqawdsqsphahgy
ipskfpnknlkknycrnpdrelrpwcfttdpnkrwelcdiprcttpck