PDB entry 2dm6
View 2dm6 on RCSB PDB site
Description: Crystal structure of anti-configuration of indomethacin and leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase complex
Class: oxidoreductase
Keywords: NAD(P)-binding Rossmann-fold domains, RIKEN Structural Genomics/Proteomics Initiative, RSGI, Structural Genomics, OXIDOREDUCTASE
Deposited on
2006-04-20, released
2006-11-28
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-10-11, with a file datestamp of
2017-10-06.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: NADP-dependent leukotriene B4 12-hydroxydehydrogenase
Species: Cavia porcellus [TaxId:10141]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2dm6a1, d2dm6a2, d2dm6a3 - Chain 'B':
Compound: NADP-dependent leukotriene B4 12-hydroxydehydrogenase
Species: Cavia porcellus [TaxId:10141]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2dm6b1, d2dm6b2, d2dm6b3 - Heterogens: NAP, IMN, TAM, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2dm6A (A:)
spefmvkakswtlkkhfqgkptqsdfelktvelpplkngevllealflsvdpymriaskr
lkegavmmgqqvarvvesknsafpagsivlaqsgwtthfisdgkgleklltewpdklpls
lalgtigmpgltayfgllevcgvkggetvlvsaaagavgsvvgqiaklkgckvvgaagsd
ekiaylkqigfdaafnyktvnsleealkkaspdgydcyfdnvggeflntvlsqmkdfgki
aicgaisvynrmdqlppgpspesiiykqlriegfivyrwqgdvrekalrdlmkwvlegki
qyhehvtkgfenmpaafiemlnganlgkavvta
Sequence, based on observed residues (ATOM records): (download)
>2dm6A (A:)
efmvkakswtlkkhfqgkptqsdfelktvelpplkngevllealflsvdpymriaskrlk
egavmmgqqvarvvesknsafpagsivlaqsgwtthfisdgkgleklltewpdklplsla
lgtigmpgltayfgllevcgvkggetvlvsaaagavgsvvgqiaklkgckvvgaagsdek
iaylkqigfdaafnyktvnsleealkkaspdgydcyfdnvggeflntvlsqmkdfgkiai
cgaisvynrmdqlppgpspesiiykqlriegfivyrwqgdvrekalrdlmkwvlegkiqy
hehvtkgfenmpaafiemlnganlgkavvta
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>2dm6B (B:)
spefmvkakswtlkkhfqgkptqsdfelktvelpplkngevllealflsvdpymriaskr
lkegavmmgqqvarvvesknsafpagsivlaqsgwtthfisdgkgleklltewpdklpls
lalgtigmpgltayfgllevcgvkggetvlvsaaagavgsvvgqiaklkgckvvgaagsd
ekiaylkqigfdaafnyktvnsleealkkaspdgydcyfdnvggeflntvlsqmkdfgki
aicgaisvynrmdqlppgpspesiiykqlriegfivyrwqgdvrekalrdlmkwvlegki
qyhehvtkgfenmpaafiemlnganlgkavvta