PDB entry 2djx

View 2djx on RCSB PDB site
Description: Crystal structure of native Trypanosoma cruzi dihydroorotate dehydrogenase
Class: oxidoreductase
Keywords: Chagas' disease, Pyrimidine biosynthesis, Fumarate reductase, Energy metabolism, Redox homeostasis, Flavoprotein, OXIDOREDUCTASE
Deposited on 2006-04-05, released 2007-06-26
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.58 Å
R-factor: 0.182
AEROSPACI score: 0.62 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydroorotate dehydrogenase
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: TCDHOD2
    Database cross-references and differences (RAF-indexed):
    • GB BAE48283 (Start-313)
      • conflict (25)
    Domains in SCOPe 2.06: d2djxa_
  • Chain 'B':
    Compound: dihydroorotate dehydrogenase
    Species: Trypanosoma cruzi [TaxId:5693]
    Gene: TCDHOD2
    Database cross-references and differences (RAF-indexed):
    • GB BAE48283 (Start-313)
      • conflict (25)
    Domains in SCOPe 2.06: d2djxb_
  • Heterogens: NCO, FMN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2djxA (A:)
mmclklnlldhvfanpfmnaagvlccteedlrcmtasssgalvsksctsaprdgnpepry
mafplgsinsmglpnlgfdfylkyasdlhdyskkplflsisglsveenvamvrrlapvaq
ekgvllelnlscpnvpgkpqvaydfeamrtylqqvslayglpfgvkmppyfdiahfdtaa
avlnefplvkfvtcvnsvgnglvidaesesvvikpkqgfgglggkyilptalanvnafyr
rcpdklvfgcggvysgedaflhilagasmvqvgtalqeegpgiftrledelleimarkgy
rtleefrgrvktie

    Sequence, based on observed residues (ATOM records): (download) 
    >2djxA (A:)
mclklnlldhvfanpfmnaagvlccteedlrcmtasssgalvsksctsaprdgnpeprym
afplgsinsmglpnlgfdfylkyasdlhdyskkplflsisglsveenvamvrrlapvaqe
kgvllelnlscpnvpgkpqvaydfeamrtylqqvslayglpfgvkmppyfdiahfdtaaa
vlnefplvkfvtcvnsvgnglvidaesesvvikpkqgfgglggkyilptalanvnafyrr
cpdklvfgcggvysgedaflhilagasmvqvgtalqeegpgiftrledelleimarkgyr
tleefrgrvktie

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2djxB (B:)
mmclklnlldhvfanpfmnaagvlccteedlrcmtasssgalvsksctsaprdgnpepry
mafplgsinsmglpnlgfdfylkyasdlhdyskkplflsisglsveenvamvrrlapvaq
ekgvllelnlscpnvpgkpqvaydfeamrtylqqvslayglpfgvkmppyfdiahfdtaa
avlnefplvkfvtcvnsvgnglvidaesesvvikpkqgfgglggkyilptalanvnafyr
rcpdklvfgcggvysgedaflhilagasmvqvgtalqeegpgiftrledelleimarkgy
rtleefrgrvktie

    Sequence, based on observed residues (ATOM records): (download) 
    >2djxB (B:)
mclklnlldhvfanpfmnaagvlccteedlrcmtasssgalvsksctsaprdgnpeprym
afplgsinsmglpnlgfdfylkyasdlhdyskkplflsisglsveenvamvrrlapvaqe
kgvllelnlscpnvpgkpqvaydfeamrtylqqvslayglpfgvkmppyfdiahfdtaaa
vlnefplvkfvtcvnsvgnglvidaesesvvikpkqgfgglggkyilptalanvnafyrr
cpdklvfgcggvysgedaflhilagasmvqvgtalqeegpgiftrledelleimarkgyr
tleefrgrvktie