PDB entry 2d9q

View 2d9q on RCSB PDB site
Description: Crystal Structure of the Human GCSF-Receptor Signaling Complex
Class: signaling protein/cytokine
Keywords: cytokine, ligand-receptor complex
Deposited on 2005-12-12, released 2006-02-07
The last revision prior to the SCOP 1.73 freeze date was dated 2006-06-20, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.253
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: csf3
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2d9qa1
  • Chain 'B':
    Compound: granulocyte colony-stimulating factor receptor
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99062
      • engineered (77)
      • engineered (162)
      • engineered (227)
    Domains in SCOP 1.73: d2d9qb1, d2d9qb2, d2d9qb3
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2d9qA (A:)
tplgpasslpqsfllkcleqvrkiqgdgaalqeklcatyklchpeelvllghslgipwap
lsscpsqalqlagclsqlhsglflyqgllqalegispelgptldtlqldvadfattiwqq
meelgmapalqptqgampafasafqrraggvlvashlqsflevsyrvlrhlaqp

    Sequence, based on observed residues (ATOM records): (download) 
    >2d9qA (A:)
sslpqsfllkcleqvrkiqgdgaalqeklcatyklchpeelvllghslgipwaplsscps
qalqlagclsqlhsglflyqgllqalegispelgptldtlqldvadfattiwqqmeelgm
apalqptqgampafasafqrraggvlvashlqsflevsyrvlrhlaqp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2d9qB (B:)
ecghisvsapivhlgdpitasciikqncshldpepqilwrlgaelqpggrqqrlsdgtqe
siitlphlnhtqaflscslnwgnslqildqvelragyppaiphnlsclmnlttsslicqw
epgpethlptsftlksfksrgncqtqgdsildcvpkdgqshcsiprkhlllyqnmgiwvq
aenalgtsmspqlcldpmdvvkleppmlrtmdpspeaappqagclqlswepwqpglhinq
kcelrhkpqrgeaswalvgplplealqyelcgllpataytlqircirwplpghwsdwsps
lelrtteraaapr

    Sequence, based on observed residues (ATOM records): (download) 
    >2d9qB (B:)
cghisvsapivhlgdpitasciikqncshldpepqilwrlgaelqpggrqqrlsdgtqes
iitlphlnhtqaflscslnwgnslqildqvelragyppaiphnlsclmnlttsslicqwe
pgpethlptsftlksfksrgncqtqgdsildcvpkdgqshcsiprkhlllyqnmgiwvqa
enalgtsmspqlcldpmdvvkleppmlrtmdpqagclqlswepwqpglhinqkcelrhkp
qrgeaswalvgplplealqyelcgllpataytlqircirwplpghwsdwspslelrtte