PDB entry 2d0t

View 2d0t on RCSB PDB site
Description: Crystal structure of 4-phenylimidazole bound form of human indoleamine 2,3-dioxygenase
Class: Oxidoreductase
Keywords: HELIX BUNDLE, RIKEN Structural Genomics/Proteomics Initiative, RSGI, Structural Genomics, Oxidoreductase
Deposited on 2005-08-08, released 2006-01-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.191
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Indoleamine 2,3-dioxygenase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2d0ta1
  • Chain 'B':
    Compound: Indoleamine 2,3-dioxygenase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2d0tb_
  • Heterogens: HEM, PIM, NHE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2d0tA (A:)
    gshmahamenswtiskeyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlre
    rveklnmlsidhltdhksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskk
    lelppilvyadcvlanwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasa
    ikviptvfkamqmqerdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgw
    kgnpqlsdglvyegfwedpkefaggsagqssvfqcfdvllgiqqtaggghaaqflqdmrr
    ymppahrnflcslesnpsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilip
    asqqpkenktsedpskleakgtggtdlmnflktvrstteksllkeg
    

    Sequence, based on observed residues (ATOM records): (download)
    >2d0tA (A:)
    skeyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidhlt
    dhksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklelppilvyadcvl
    anwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamqmq
    erdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvyeg
    fwedpkefaggsagqssvfqcfdvllgiqqtaggghaaqflqdmrrymppahrnflcsle
    snpsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipasqggtdlmnflkt
    vrstteksllkeg
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2d0tB (B:)
    gshmahamenswtiskeyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlre
    rveklnmlsidhltdhksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskk
    lelppilvyadcvlanwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasa
    ikviptvfkamqmqerdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgw
    kgnpqlsdglvyegfwedpkefaggsagqssvfqcfdvllgiqqtaggghaaqflqdmrr
    ymppahrnflcslesnpsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilip
    asqqpkenktsedpskleakgtggtdlmnflktvrstteksllkeg
    

    Sequence, based on observed residues (ATOM records): (download)
    >2d0tB (B:)
    iskeyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidhl
    tdhksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklelppilvyadcv
    lanwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamqm
    qerdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvye
    gfwedpkefaggsagqssvfqcfdvllgiqqtaggghaaqflqdmrrymppahrnflcsl
    esnpsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipasqggtdlmnflk
    tvrstteksllkeg