PDB entry 2cy4

View 2cy4 on RCSB PDB site
Description: Crystal structure of phosphotyrosine binding (PTB) domain of epidermal growth factor receptor pathway substrate-8 (EPS8) related protein 1 from Mus musculus (form-1 crystal)
Class: signaling protein
Keywords: structural genomics, signal transduction, phosphorylation, PTB domain, NPPSFA, National Project on Protein Structural and Functional Analyses, RIKEN Structural Genomics/Proteomics Initiative, RSGI
Deposited on 2005-07-04, released 2006-01-04
The last revision prior to the SCOP 1.73 freeze date was dated 2006-01-04, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.94 Å
R-factor: 0.209
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: epidermal growth factor receptor pathway substrate 8-like protein 1
    Species: MUS MUSCULUS
    Database cross-references and differences (RAF-indexed):
    • GB NP_080422
      • modified residue (39)
      • modified residue (50)
      • modified residue (85)
    Domains in SCOP 1.73: d2cy4a1
  • Heterogens: CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2cy4A (A:)
    stvvmadvsqyhvnhlvtfclgeedgvhtvedasrklavmdsqgrvwaqemllrvspsqv
    tlldpvskeelesypldaivrcdavmprgrsrsllllvcqeperaqpdvhffqglllgae
    lirediqgalqnyrsgrger
    

    Sequence, based on observed residues (ATOM records): (download)
    >2cy4A (A:)
    advsqyhvnhlvtfclgeedgvhtvedasrklavmdsqgrvwaqemllrvspsqvtlldp
    vskeelesypldaivrcdavmprgrsrsllllvcqeperaqpdvhffqglllgaelired
    iqgalqnyr