PDB entry 2cxv

View 2cxv on RCSB PDB site
Description: Dual Modes of Modification of Hepatitis A Virus 3C Protease by a Serine-Derived betaLactone: Selective Crystallization and High-resolution Structure of the His-102 Adduct
Class: hydrolase
Keywords: Hepatitis A, picornavirus, 3C, cysteine protease, inhibitor, beta-Lactone, HYDROLASE
Deposited on 2005-07-01, released 2005-12-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: 0.186
AEROSPACI score: 0.67 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Probable protein P3C
    Species: Human hepatitis A virus Hu/Northern Africa/MBB/1978 [TaxId:12100]
    Gene: 3C
    Database cross-references and differences (RAF-indexed):
    • Uniprot P13901 (0-End)
      • engineered (23)
    Domains in SCOPe 2.08: d2cxva_
  • Heterogens: BBL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2cxvA (A:)
stleiaglvrknlvqfgvgekngsvrwvmnalgvkddwllvpshaykfekdyemmefyfn
rggtyysisagnvviqsldvgfqdvvlmkvptipkfrditqhfikkgdvpralnrlatlv
ttvngtpmlisegplkmeekatyvhkkndgttvdltvdqawrgkgeglpgmcggalvssn
qsiqnailgihvaggnsilvaklvtqemfqnidkkiesq

    Sequence, based on observed residues (ATOM records): (download) 
    >2cxvA (A:)
stleiaglvrknlvqfgvgekngsvrwvmnalgvkddwllvpshaykfekdyemmefyfn
rggtyysisagnvviqsldvgfqdvvlmkvptipkfrditqhfikkgdvpralnrlatlv
ttvngtpmlisegplkmeekatyvhkkndgttvdltvdqawrgkgeglpgmcggalvssn
qsiqnailgihvaggnsilvaklvtqemfqni