PDB entry 2cog

View 2cog on RCSB PDB site
Description: Crystal structure of oxidized human cytosolic branched-chain aminotransferase complexed with 4-methylvalerate
Class: transferase
Keywords: PLP-dependent enzyme, TRANSFERASE
Deposited on 2005-05-17, released 2005-08-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.233
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: branched chain aminotransferase 1, cytosolic
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P54687
      • engineered (378)
    Domains in SCOPe 2.08: d2coga_
  • Chain 'B':
    Compound: branched chain aminotransferase 1, cytosolic
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P54687
      • engineered (378)
    Domains in SCOPe 2.08: d2cogb_
  • Heterogens: MG, PLP, 4MV, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2cogA (A:)
mkdcsngcsaectgeggskevvgtfkakdlivtpatilkekpdpnnlvfgtvftdhmltv
ewssefgwekphikplqnlslhpgssalhyavelfeglkafrgvdnkirlfqpnlnmdrm
yrsavratlpvfdkeelleciqqlvkldqewvpystsaslyirptfigtepslgvkkptk
allfvllspvgpyfssgtfnpvslwanpkyvrawkggtgdckmggnygsslfaqceavdn
gcqqvlwlygedhqitevgtmnlflywinedgeeelatppldgiilpgvtrrcildlahq
wgefkvseryltmddlttalegnrvremfgsgtacvvcpvsdilykgetihiptmengpk
lasrilskltdiqygreerdwtivls

    Sequence, based on observed residues (ATOM records): (download) 
    >2cogA (A:)
vgtfkakdlivtpatilkekpdpnlvfgtvftdhmltvewssefgwekphikplqnlslh
pgssalhyavelfeglkafrgvdnkirlfqpnlnmdrmyrsavratlpvfdkeelleciq
qlvkldqewvpystsaslyirptfigtepslgvkkptkallfvllspvgpyfnpvslwan
pkyvrawkggtgdckmggnygsslfaqceavdngcqqvlwlygedhqitevgtmnlflyw
inedgeeelatppldgiilpgvtrrcildlahqwgefkvseryltmddlttalegnrvre
mfgsgtacvvcpvsdilykgetihiptmengpklasrilskltdiqygreerdwtivl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2cogB (B:)
mkdcsngcsaectgeggskevvgtfkakdlivtpatilkekpdpnnlvfgtvftdhmltv
ewssefgwekphikplqnlslhpgssalhyavelfeglkafrgvdnkirlfqpnlnmdrm
yrsavratlpvfdkeelleciqqlvkldqewvpystsaslyirptfigtepslgvkkptk
allfvllspvgpyfssgtfnpvslwanpkyvrawkggtgdckmggnygsslfaqceavdn
gcqqvlwlygedhqitevgtmnlflywinedgeeelatppldgiilpgvtrrcildlahq
wgefkvseryltmddlttalegnrvremfgsgtacvvcpvsdilykgetihiptmengpk
lasrilskltdiqygreerdwtivls

    Sequence, based on observed residues (ATOM records): (download) 
    >2cogB (B:)
tfkakdlivtpatilkekpdpnnlvfgtvftdhmltvewssefgwekphikplqnlslhp
gssalhyavelfeglkafrgvdnkirlfqpnlnmdrmyrsavratlpvfdkeelleciqq
lvkldqewvpystsaslyirptfigtepslgvkkptkallfvllspvgpyffnpvslwan
pkyvrawkggtgdckmggnygsslfaqceavdngcqqvlwlygedhqitevgtmnlflyw
inedgeeelatppldgiilpgvtrrcildlahqwgefkvseryltmddlttalegnrvre
mfgsgtacvvcpvsdilykgetihiptmengpklasrilskltdiqygreerdwtivl