PDB entry 2cnb

View 2cnb on RCSB PDB site
Description: trypanosoma brucei udp-galactose-4-epimerase in ternary complex with nad and the substrate analogue udp-4-deoxy-4-fluoro-alpha-d-galactose
Class: epimerase
Keywords: short-chain dehydrogenase/reductase, udp-galactose-4-epimerase, nad, isomerase, trypanosoma brucei, udp-4-deoxy- 4-fluoro-alpha-d-galactose
Deposited on 2006-05-18, released 2006-06-12
The last revision prior to the SCOP 1.73 freeze date was dated 2007-01-03, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.203
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: udp-galactose-4-epimerase
    Species: Trypanosoma brucei
    Database cross-references and differences (RAF-indexed):
    • PDB 2CNB (0-1)
    • Uniprot Q8T8E9 (2-End)
    Domains in SCOP 1.73: d2cnba1
  • Chain 'B':
    Compound: udp-galactose-4-epimerase
    Species: Trypanosoma brucei
    Database cross-references and differences (RAF-indexed):
    • PDB 2CNB (0-1)
    • Uniprot Q8T8E9 (2-End)
    Domains in SCOP 1.73: d2cnbb1
  • Chain 'C':
    Compound: udp-galactose-4-epimerase
    Species: Trypanosoma brucei
    Database cross-references and differences (RAF-indexed):
    • PDB 2CNB (0-1)
    • Uniprot Q8T8E9 (2-End)
    Domains in SCOP 1.73: d2cnbc1
  • Chain 'D':
    Compound: udp-galactose-4-epimerase
    Species: Trypanosoma brucei
    Database cross-references and differences (RAF-indexed):
    • PDB 2CNB (0-1)
    • Uniprot Q8T8E9 (2-End)
    Domains in SCOP 1.73: d2cnbd1
  • Heterogens: UFG, NAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2cnbA (A:)
shmrvlvcggagyigshfvrallrdtnhsvvivdslvgthgksdhvetrenvarklqqsd
gpkppwadryaalevgdvrnedflngvftrhgpidavvhmcaflavgesvrdplkyydnn
vvgilrllqamllhkcdkiifsssaaifgnptmgsvstnaepidinakkspespygeskl
iaermirdcaeaygikgiclryfnacgahedgdigehyqgsthlipiilgrvmsdiapdq
rltihedastdkrmpifgtdyptpdgtcvrdyvhvcdlasahilaldyveklgpndksky
fsvfnlgtsrgysvrevievarkttghpipvrecgrregdpaylvaasdkarevlgwkpk
ydtleaimetswkfqrthpngyasqengtpggrttkl

    Sequence, based on observed residues (ATOM records): (download) 
    >2cnbA (A:)
shmrvlvcggagyigshfvrallrdtnhsvvivdslvgthgksdhvetrenvarklqqsd
gpkppwadryaalevgdvrnedflngvftrhgpidavvhmcaflavgesvrdplkyydnn
vvgilrllqamllhkcdkiifsssaaifgnptnaepidinakkspespygeskliaermi
rdcaeaygikgiclryfnacgahedgdigehyqgsthlipiilgrvmsdiapddkrmpif
gtdyptpdgtcvrdyvhvcdlasahilaldyveklgpndkskyfsvfnlgtsrgysvrev
ievarkttghpipvrecgrregdpaylvaasdkarevlgwkpkydtleaimetswkfqrt
hpngya

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2cnbB (B:)
shmrvlvcggagyigshfvrallrdtnhsvvivdslvgthgksdhvetrenvarklqqsd
gpkppwadryaalevgdvrnedflngvftrhgpidavvhmcaflavgesvrdplkyydnn
vvgilrllqamllhkcdkiifsssaaifgnptmgsvstnaepidinakkspespygeskl
iaermirdcaeaygikgiclryfnacgahedgdigehyqgsthlipiilgrvmsdiapdq
rltihedastdkrmpifgtdyptpdgtcvrdyvhvcdlasahilaldyveklgpndksky
fsvfnlgtsrgysvrevievarkttghpipvrecgrregdpaylvaasdkarevlgwkpk
ydtleaimetswkfqrthpngyasqengtpggrttkl

    Sequence, based on observed residues (ATOM records): (download) 
    >2cnbB (B:)
shmrvlvcggagyigshfvrallrdtnhsvvivdslvgthgksdhvetrenvarklqqsd
gpkppwadryaalevgdvrnedflngvftrhgpidavvhmcaflavgesvrdplkyydnn
vvgilrllqamllhkcdkiifsssaaifgnptaepidinakkspespygeskliaermir
dcaeaygikgiclryfnacgahedgdigehyqgsthlipiilgrvmsdiadkrmpifgtd
yptpdgtcvrdyvhvcdlasahilaldyveklgpndkskyfsvfnlgtsrgysvreviev
arkttghpipvrecgrregdpaylvaasdkarevlgwkpkydtleaimetswkfqrthpn
gya

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2cnbC (C:)
shmrvlvcggagyigshfvrallrdtnhsvvivdslvgthgksdhvetrenvarklqqsd
gpkppwadryaalevgdvrnedflngvftrhgpidavvhmcaflavgesvrdplkyydnn
vvgilrllqamllhkcdkiifsssaaifgnptmgsvstnaepidinakkspespygeskl
iaermirdcaeaygikgiclryfnacgahedgdigehyqgsthlipiilgrvmsdiapdq
rltihedastdkrmpifgtdyptpdgtcvrdyvhvcdlasahilaldyveklgpndksky
fsvfnlgtsrgysvrevievarkttghpipvrecgrregdpaylvaasdkarevlgwkpk
ydtleaimetswkfqrthpngyasqengtpggrttkl

    Sequence, based on observed residues (ATOM records): (download) 
    >2cnbC (C:)
shmrvlvcggagyigshfvrallrdtnhsvvivdslvgthgksdhvetrenvarklqqsd
gpkppwadryaalevgdvrnedflngvftrhgpidavvhmcaflavgesvrdplkyydnn
vvgilrllqamllhkcdkiifsssaaifgnptaepidinakkspespygeskliaermir
dcaeaygikgiclryfnacgahedgdigehyqgsthlipiilgrvmsdiapdtdkrmpif
gtdyptpdgtcvrdyvhvcdlasahilaldyveklgpndkskyfsvfnlgtsrgysvrev
ievarkttghpipvrecgrregdpaylvaasdkarevlgwkpkydtleaimetswkfqrt
hpngya

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2cnbD (D:)
shmrvlvcggagyigshfvrallrdtnhsvvivdslvgthgksdhvetrenvarklqqsd
gpkppwadryaalevgdvrnedflngvftrhgpidavvhmcaflavgesvrdplkyydnn
vvgilrllqamllhkcdkiifsssaaifgnptmgsvstnaepidinakkspespygeskl
iaermirdcaeaygikgiclryfnacgahedgdigehyqgsthlipiilgrvmsdiapdq
rltihedastdkrmpifgtdyptpdgtcvrdyvhvcdlasahilaldyveklgpndksky
fsvfnlgtsrgysvrevievarkttghpipvrecgrregdpaylvaasdkarevlgwkpk
ydtleaimetswkfqrthpngyasqengtpggrttkl

    Sequence, based on observed residues (ATOM records): (download) 
    >2cnbD (D:)
shmrvlvcggagyigshfvrallrdtnhsvvivdslvgthgksdhvetrenvarklqqsd
gpkppwadryaalevgdvrnedflngvftrhgpidavvhmcaflavgesvrdplkyydnn
vvgilrllqamllhkcdkiifsssaaifgnptnaepidinakkspespygeskliaermi
rdcaeaygikgiclryfnacgahedgdigehyqgsthlipiilgrvmsdiadkrmpifgt
dyptpdgtcvrdyvhvcdlasahilaldyveklgpndkskyfsvfnlgtsrgysvrevie
varkttghpipvrecgrregdpaylvaasdkarevlgwkpkydtleaimetswkfqrthp
ngya