PDB entry 2cmw
View 2cmw on RCSB PDB site
Description: structure of human casein kinase 1 gamma-1 in complex with 2-(2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine (casp target)
Class: transferase
Keywords: wnt signaling pathway, serine/threonine-protein kinase, kinase, transferase, ATP-binding, phosphorylation, nucleotide-binding, serine/threonine protein kinase
Deposited on
2006-05-15, released
2006-06-15
The last revision prior to the SCOPe 2.05 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-31.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.167
AEROSPACI score: 0.54
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: casein kinase I isoform gamma-1
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- PDB 2CMW (Start-1)
- Uniprot Q9HCP0 (2-End)
Domains in SCOPe 2.05: d2cmwa_ - Heterogens: OLP, PO4, ACT, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2cmwA (A:)
smrvgkkigcgnfgelrlgknlytneyvaiklepiksrapqlhleyrfykqlgsageglp
qvyyfgpcgkynamvlellgpsledlfdlcdrtftlktvlmiaiqllsrmeyvhsknliy
rdvkpenfligrqgnkkehvihiidfglakeyidpetkkhipyrehksltgtarymsint
hlgkeqsrrddlealghmfmyflrgslpwqglkadtlkeryqkigdtkrntpiealcenf
peematylryvrrldffekpdyeylrtlftdlfekkgytfdyaydwvgrpiptpvgsvhv
dsgasaitre
Sequence, based on observed residues (ATOM records): (download)
>2cmwA (A:)
mrvgkkigcgnfgelrlgknlytneyvaiklepiksrapqlhleyrfykqlgsageglpq
vyyfgpcgkynamvlellgpsledlfdlcdrtftlktvlmiaiqllsrmeyvhsknliyr
dvkpenfligrqgnkkehvihiidfglakeyidpetkkhipyrehkslgtarymsinthl
gkeqsrrddlealghmfmyflrgslpwqglkadtlkeryqkigdtkrntpiealcenfpe
ematylryvrrldffekpdyeylrtlftdlfekkgytfdyaydwvgrpiptpvgs