PDB entry 2cm3

View 2cm3 on RCSB PDB site
Description: structure of protein tyrosine phosphatase 1b (c2)
Class: hydrolase
Keywords: polymorphism, phosphorylation, protein phosphatase, endoplasmic reticulum, oxidation, hydrolase, acetylation, phosphatase
Deposited on 2006-05-04, released 2006-08-17
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.2334
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tyrosine-protein phosphatase non-receptor type 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2cm3a_
  • Chain 'B':
    Compound: tyrosine-protein phosphatase non-receptor type 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2cm3b_
  • Heterogens: CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2cm3A (A:)
    mhhhhhhemekefeqidksgswaaiyqdirheasdfpcrvaklpknknrnryrdvspfdh
    sriklhqedndyinaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvvmlnrvm
    ekgslkcaqywpqkeekemifedtnlkltlisediksyytvrqlelenlttqetreilhf
    hyttwpdfgvpespasflnflfkvresgslspehgpvvvhcsagigrsgtfcladtclll
    mdkrkdpssvdikkvllemrkfrmgliqtadqlrfsylaviegakfimgdssvqdqwkel
    shed
    

    Sequence, based on observed residues (ATOM records): (download)
    >2cm3A (A:)
    feqidksgswaaiyqdirheasdfpcrvaklpknknrnryrdvspfdhsriklhqedndy
    inaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvvmlnrvmekgslkcaqywp
    qkeekemifedtnlkltlisediksyytvrqlelenlttqetreilhfhyttwpdfgvpe
    spasflnflfkvresgslspehgpvvvhcsagigrsgtfcladtclllmdkrkdpssvdi
    kkvllemrkfrmgliqtadqlrfsylaviegakfi
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2cm3B (B:)
    mhhhhhhemekefeqidksgswaaiyqdirheasdfpcrvaklpknknrnryrdvspfdh
    sriklhqedndyinaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvvmlnrvm
    ekgslkcaqywpqkeekemifedtnlkltlisediksyytvrqlelenlttqetreilhf
    hyttwpdfgvpespasflnflfkvresgslspehgpvvvhcsagigrsgtfcladtclll
    mdkrkdpssvdikkvllemrkfrmgliqtadqlrfsylaviegakfimgdssvqdqwkel
    shed
    

    Sequence, based on observed residues (ATOM records): (download)
    >2cm3B (B:)
    feqidksgswaaiyqdirheasdfpcrvaklpknknrnryrdvspfdhsriklhqedndy
    inaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvvmlnrvmekgslkcaqywp
    qkeekemifedtnlkltlisediksyytvrqlelenlttqetreilhfhyttwpdfgvpe
    spasflnflfkvresgslspehgpvvvhcsagigrsgtfcladtclllmdkrkdpssvdi
    kkvllemrkfrmgliqtadqlrfsylaviegakfi