PDB entry 2clx

View 2clx on RCSB PDB site
Description: 4-Arylazo-3,5-diamino-1H-pyrazole CDK Inhibitors: SAR Study, Crystal Structure in Complex with CDK2, Selectivity, and Cellular Effects
Class: transferase
Keywords: transferase, serine/threonine- protein kinase, phosphorylation, nucleotide-binding, cdk2, kinase, mitosis, cell cycle, ATP-binding, polymorphism, cell division, serine-threonine-protein kinase
Deposited on 2006-05-02, released 2006-11-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-01-30, with a file datestamp of 2019-01-25.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2clxa_
  • Heterogens: F18, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2clxA (A:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

    Sequence, based on observed residues (ATOM records): (download) 
    >2clxA (A:)
menfqkvekigegtygvvykarnkltgevvalkkirlgvpstaireisllkelnhpnivk
lldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlh
rdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyystavd
iwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwar
qdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl