PDB entry 2cij

View 2cij on RCSB PDB site
Description: membrane-bound glutamate carboxypeptidase II (GCPII) with bound methionine
Class: hydrolase
Keywords: neurodegenerative disease, peptidase, prostate cancer, psma, glycoprotein, hydrolase, antigen, metal-binding, metalloprotease, multifunctional enzyme, signal-anchor, transmembrane
Deposited on 2006-03-21, released 2007-03-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glutamate carboxypeptidase II
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2cija1, d2cija2, d2cija3
  • Heterogens: MET, ZN, CA, CL, NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2cijA (A:)
kssneatnitpkhnmkafldelkaenikkflynftqiphlagteqnfqlakqiqsqwkef
gldsvelahydvllsypnkthpnyisiinedgneifntslfeppppgyenvsdivppfsa
fspqgmpegdlvyvnyartedffklerdmkincsgkiviarygkvfrgnkvknaqlagak
gvilysdpadyfapgvksypdgwnlpgggvqrgnilnlngagdpltpgypaneyayrrgi
aeavglpsipvhpigyydaqkllekmggsappdsswrgslkvpynvgpgftgnfstqkvk
mhihstnevtriynvigtlrgavepdryvilgghrdswvfggidpqsgaavvheivrsfg
tlkkegwrprrtilfaswdaeefgllgstewaeensrllqergvayinadssiegnytlr
vdctplmyslvhnltkelkspdegfegkslyeswtkkspspefsgmprisklgsgndfev
ffqrlgiasgrarytknwetnkfsgyplyhsvyetyelvekfydpmfkyhltvaqvrggm
vfelansivlpfdcrdyavvlrkyadkiysismkhpqemktysvsfdslfsavknfteia
skfserlqdfdksnpivlrmmndqlmflerafidplglpdrpfyrhviyapsshnkyage
sfpgiydalfdieskvdpskawgevkrqiyvaaftvqaaaetlseva

    Sequence, based on observed residues (ATOM records): (download) 
    >2cijA (A:)
nmkafldelkaenikkflynftqiphlagteqnfqlakqiqsqwkefgldsvelahydvl
lsypnkthpnyisiinedgneifntslfeppppgyenvsdivppfsafspqgmpegdlvy
vnyartedffklerdmkincsgkiviarygkvfrgnkvknaqlagakgvilysdpadyfa
pgvksypdgwnlpgggvqrgnilnlngagdpltpgypaneyayrrgiaeavglpsipvhp
igyydaqkllekmggsappdsswrgslkvpynvgpgftfstqkvkmhihstnevtriynv
igtlrgavepdryvilgghrdswvfggidpqsgaavvheivrsfgtlkkegwrprrtilf
aswdaeefgllgstewaeensrllqergvayinadssiegnytlrvdctplmyslvhnlt
kelkspdegfegkslyeswtkkspspefsgmprisklgsgndfevffqrlgiasgraryt
knfsgyplyhsvyetyelvekfydpmfkyhltvaqvrggmvfelansivlpfdcrdyavv
lrkyadkiysismkhpqemktysvsfdslfsavknfteiaskfserlqdfdksnpivlrm
mndqlmflerafidplglpdrpfyrhviyapsshnkyagesfpgiydalfdieskvdpsk
awgevkrqiyvaaftvqaaaetlseva