PDB entry 2cft

View 2cft on RCSB PDB site
Description: crystal structure of human pyridoxal 5'-phosphate phosphatase with its substrate
Class: phosphatase
Keywords: phosphatase, chronophin, had family, hydrolase, magnesium, metal-binding, pyridoxal phosphate
Deposited on 2006-02-23, released 2007-02-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.187
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: pyridoxal phosphate phosphatase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2CFT
    • Uniprot Q96GD0 (2-End)
    Domains in SCOPe 2.08: d2cfta_
  • Heterogens: PLP, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2cftA (A:)
gamarcerlrgaalrdvlgraqgvlfdcdgvlwngeravpgapellerlaragkaalfvs
nnsrrarpelalrfarlgfgglraeqlfssalcaarllrqrlpgppdapgavfvlggegl
raelraaglrlagdpsagdgaaprvravlvgydehfsfaklreacahlrdpecllvatdr
dpwhplsdgsrtpgtgslaaavetasgrqalvvgkpspymfecitenfsidpartlmvgd
rletdilfghrcgmttvltltgvsrleeaqaylaagqhdlvphyyvesiadltegled

    Sequence, based on observed residues (ATOM records): (download) 
    >2cftA (A:)
marcerlrgaalrdvlgraqgvlfdcdgvlwngeravpgapellerlaragkaalfvsnn
srrarpelalrfarlgfgglraeqlfssalcaarllrqrlpgppdgavfvlggeglrael
raaglrlagdpsagdgaaprvravlvgydehfsfaklreacahlrdpecllvatdrdpwh
plsdgsrtpgtgslaaavetasgrqalvvgkpspymfecitenfsidpartlmvgdrlet
dilfghrcgmttvltltgvsrleeaqaylaagqhdlvphyyvesiadltegle