PDB entry 2cff

View 2cff on RCSB PDB site
Description: Crystal Structure Of N-((5'-Phosphoribosyl)-Formimino)-5- Aminoimidazol-4-Carboxamid Ribonucleotid Isomerase mutant D127V (Ec 3. 1.3.15, Hisa)
Class: isomerase
Keywords: isomerase, histidine biosynthesis, thermophilic protein, amino-acid biosynthesis
Deposited on 2006-02-20, released 2007-03-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-03-29, with a file datestamp of 2017-03-24.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino) methylideneamino] imidazole-4-carboxamide isomerase
    Species: Thermotoga maritima [TaxId:2336]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9X0C7 (0-240)
      • engineered mutation (126)
    Domains in SCOPe 2.07: d2cffa_
  • Chain 'B':
    Compound: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino) methylideneamino] imidazole-4-carboxamide isomerase
    Species: Thermotoga maritima [TaxId:2336]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9X0C7 (0-240)
      • engineered mutation (126)
    Domains in SCOPe 2.07: d2cffb_
  • Heterogens: MPD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2cffA (A:)
mlvvpaidlfrgkvarmikgrkentifyekdpvelveklieegftlihvvdlsnaiensg
enlpvleklsefaehiqigggirsldyaeklrklgyrrqivsskvledpsflkslreidv
epvfslvtrggrvafkgwlaeeeidpvsllkrlkeygleeivhteiekdgtlqehdfslt
kkiaieaevkvlaaggissenslktaqkvhtetngllkgvivgraflegiltvevmkrya
r

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2cffB (B:)
mlvvpaidlfrgkvarmikgrkentifyekdpvelveklieegftlihvvdlsnaiensg
enlpvleklsefaehiqigggirsldyaeklrklgyrrqivsskvledpsflkslreidv
epvfslvtrggrvafkgwlaeeeidpvsllkrlkeygleeivhteiekdgtlqehdfslt
kkiaieaevkvlaaggissenslktaqkvhtetngllkgvivgraflegiltvevmkrya
r