PDB entry 2cdd

View 2cdd on RCSB PDB site
Description: human hsp90 with 4-(4-(2,3-dihydro-benzol(1,4)dioxin-6-yl)-5-methyl-1h-pyrazol-3-yl)-6-ethyl-benzene-1,3-diol
Class: heat-shock protein complex
Keywords: hsp90, ATPase, pyrazole, chaperone, ATP-binding, heat shock, chaperone, nucleotide-binding, phosphorylation
Deposited on 2006-01-23, released 2006-02-15
The last revision prior to the SCOP 1.73 freeze date was dated 2006-03-08, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.20387
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: heat shock protein hsp-90 alpha
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2cdda1
  • Chain 'B':
    Compound: heat shock protein hsp-90 alpha
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2cddb1
  • Heterogens: CT5, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2cddA (A:)
mpeetqtqdqpmeeeevetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkir
yesltdpskldsgkelhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafme
alqagadismigqfgvgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepm
grgtkvilhlkedqteyleerrikeivkkhsqfigypitlfvekerdkevsddeae

    Sequence, based on observed residues (ATOM records): (download) 
    >2cddA (A:)
evetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltdpskldsgke
lhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadismigqfg
vgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhlkedqt
eyleerrikeivkkhsqfigypitlfvek

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2cddB (B:)
mpeetqtqdqpmeeeevetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkir
yesltdpskldsgkelhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafme
alqagadismigqfgvgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepm
grgtkvilhlkedqteyleerrikeivkkhsqfigypitlfvekerdkevsddeae

    Sequence, based on observed residues (ATOM records): (download) 
    >2cddB (B:)
evetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltdpskldsgke
lhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadismigqfg
vgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhlkedqt
eyleerrikeivkkhsqfigypitlfvek