PDB entry 2caz

View 2caz on RCSB PDB site
Description: ESCRT-I core
Class: protein transport
Keywords: protein transport, escrt, mvb, multivesicular bodies, endosome, lysosome, ph domain, protein sorting, vesicle trafficking, ubiquitin, phosphoinositide, ptdins3p, vps23, vps28, vps37, vps36, coiled coil, ubl conjugation pathway
Deposited on 2005-12-23, released 2006-04-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-08, with a file datestamp of 2019-05-03.
Experiment type: XRAY
Resolution: 3.6 Å
R-factor: N/A
AEROSPACI score: 0.06 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: suppressor protein stp22 of temperature-sensitive alpha-factor receptor and arginine permease
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2caza1
  • Chain 'B':
    Compound: vacuolar protein sorting-associated protein vps28
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2cazb1
  • Chain 'C':
    Compound: protein srn2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • PDB 2CAZ
      • conflict (11)
      • conflict (14)
    • Uniprot Q99176
    Domains in SCOPe 2.08: d2cazc1
  • Chain 'D':
    Compound: suppressor protein stp22 of temperature-sensitive alpha-factor receptor and arginine permease
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • PDB 2CAZ
    • Uniprot P25604 (Start-81)
    Domains in SCOPe 2.08: d2cazd1
  • Chain 'E':
    Compound: vacuolar protein sorting-associated protein vps28
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2caze1
  • Chain 'F':
    Compound: protein srn2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2cazA (A:)
mstshvddedvnsiavaktdglnqlynlvaqdyaltdtieclsrmlhrgtipldtfvkqg
relarqqflvrwhiqritspls

    Sequence, based on observed residues (ATOM records): (download) 
    >2cazA (A:)
lnqlynlvaqdyaltdtieclsrmlhrgtipldtfvkqgrelarqqflvrwhiqritsp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2cazB (B:)
mahhhhhhmqkhniklnqnqdisqlfhdevplfdnsitskdkevietlseiysivitldh
vekaylkdsiddtqytntvdkllkqfkvylnsqnkeeinkhfqsieafcdtynitasnai
trlergipitaehaistttsapsgdnkqssssdkk

    Sequence, based on observed residues (ATOM records): (download) 
    >2cazB (B:)
plfdnsitskdkevietlseiysivitldhvekaylkdsiddtqytntvdkllkqfkvyl
nsqnkeeinkhfqsieafcdtynitasnaitrlergipita

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2cazC (C:)
myvaswqdyhsdfsekygdialkkkleqntkkldeessqletttrsidsaddldqfikny
ldirtqyhlrreklatwdkqgnlky

    Sequence, based on observed residues (ATOM records): (download) 
    >2cazC (C:)
sdfsekygdialkkkleqntkkldeessqletttrsidsaddldqfiknyldirtqyhlr
rekla

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2cazD (D:)
mstshvddedvnsiavaktdglnqlynlvaqdyaltdtieclsrmlhrgtipldtfvkqg
relarqqflvrwhiqritspls

    Sequence, based on observed residues (ATOM records): (download) 
    >2cazD (D:)
lnqlynlvaqdyaltdtieclsrmlhrgtipldtfvkqgrelarqqflvrwhiqritspl
s

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2cazE (E:)
mahhhhhhmqkhniklnqnqdisqlfhdevplfdnsitskdkevietlseiysivitldh
vekaylkdsiddtqytntvdkllkqfkvylnsqnkeeinkhfqsieafcdtynitasnai
trlergipitaehaistttsapsgdnkqssssdkk

    Sequence, based on observed residues (ATOM records): (download) 
    >2cazE (E:)
vplfdnsitskdkevietlseiysivitldhvekaylkdsiddtqytntvdkllkqfkvy
lnsqnkeeinkhfqsieafcdtynitasnaitrlergipita

  • Chain 'F':
    No sequence available.