PDB entry 2car

View 2car on RCSB PDB site
Description: crystal structure of human inosine triphosphatase
Class: hydrolase
Keywords: inosine triphosphate pyrophosphohydrolase, inosine triphosphatase deficiency, itp, imp, disease mutation, hydrolase, nucleotide metabolism
Deposited on 2005-12-22, released 2006-01-04
The last revision prior to the SCOP 1.73 freeze date was dated 2006-01-04, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.09 Å
R-factor: 0.0974
AEROSPACI score: 0.94 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: inosine triphosphate pyrophosphatase
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2cara1
  • Chain 'B':
    Compound: inosine triphosphate pyrophosphatase
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2carb1
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2carA (A:)
gsmaaslvgkkivfvtgnakkleevvqilgdkfpctlvaqkidlpeyqgepdeisiqkcq
eavrqvqgpvlvedtclcfnalgglpgpyikwfleklkpeglhqllagfedksayalctf
alstgdpsqpvrlfrgrtsgrivaprgcqdfgwdpcfqpdgyeqtyaempkaeknavshr
frallelqeyfgslaa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2carB (B:)
gsmaaslvgkkivfvtgnakkleevvqilgdkfpctlvaqkidlpeyqgepdeisiqkcq
eavrqvqgpvlvedtclcfnalgglpgpyikwfleklkpeglhqllagfedksayalctf
alstgdpsqpvrlfrgrtsgrivaprgcqdfgwdpcfqpdgyeqtyaempkaeknavshr
frallelqeyfgslaa

    Sequence, based on observed residues (ATOM records): (download) 
    >2carB (B:)
maaslvgkkivfvtgnakkleevvqilgdkfpctlvaqkidlpeyqgepdeisiqkcqea
vrqvqgpvlvedtclcfnalgglpgpyikwfleklkpeglhqllagfedksayalctfal
stgdpsqpvrlfrgrtsgrivaprgcqdfgwdpcfqpdgyeqtyaempkaeknavshrfr
allelqeyfgslaa