PDB entry 2c9t

View 2c9t on RCSB PDB site
Description: crystal structure of acetylcholine binding protein (achbp) from aplysia californica in complex with alpha-conotoxin imi
Class: receptor/toxin
Keywords: receptor/toxin, receptor/toxin complex, acetylcholine binding protein, nicotinic acetylcholine receptor/toxin complex, conformational flexibility, conotoxin, acetylcholine receptor inhibitor, amidation, neurotoxin, postsynaptic neurotoxin, toxin
Deposited on 2005-12-14, released 2006-02-13
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.171
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8 (0-End)
      • conflict (40)
      • conflict (135)
    Domains in SCOPe 2.06: d2c9ta_
  • Chain 'B':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8 (0-End)
      • conflict (40)
      • conflict (135)
    Domains in SCOPe 2.06: d2c9tb_
  • Chain 'C':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8 (0-End)
      • conflict (40)
      • conflict (135)
    Domains in SCOPe 2.06: d2c9tc_
  • Chain 'D':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8 (0-End)
      • conflict (40)
      • conflict (135)
    Domains in SCOPe 2.06: d2c9td_
  • Chain 'E':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8 (0-End)
      • conflict (40)
      • conflict (135)
    Domains in SCOPe 2.06: d2c9te_
  • Chain 'F':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8 (0-End)
      • conflict (40)
      • conflict (135)
    Domains in SCOPe 2.06: d2c9tf_
  • Chain 'G':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8 (0-End)
      • conflict (40)
      • conflict (135)
    Domains in SCOPe 2.06: d2c9tg_
  • Chain 'H':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8 (0-End)
      • conflict (40)
      • conflict (135)
    Domains in SCOPe 2.06: d2c9th_
  • Chain 'I':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8 (0-End)
      • conflict (40)
      • conflict (135)
    Domains in SCOPe 2.06: d2c9ti_
  • Chain 'J':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8 (0-End)
      • conflict (40)
      • conflict (135)
    Domains in SCOPe 2.06: d2c9tj_
  • Chain 'K':
    Compound: alpha-conotoxin imi
    Species: CONUS IMPERIALIS [TaxId:35631]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50983 (0-11)
    • PDB 2C9T
  • Chain 'M':
    Compound: alpha-conotoxin imi
    Species: CONUS IMPERIALIS [TaxId:35631]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50983 (0-11)
    • PDB 2C9T
  • Chain 'O':
    Compound: alpha-conotoxin imi
    Species: CONUS IMPERIALIS [TaxId:35631]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50983 (0-11)
    • PDB 2C9T
  • Chain 'P':
    Compound: alpha-conotoxin imi
    Species: CONUS IMPERIALIS [TaxId:35631]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50983 (0-11)
    • PDB 2C9T
  • Chain 'Q':
    Compound: alpha-conotoxin imi
    Species: CONUS IMPERIALIS [TaxId:35631]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50983 (0-11)
    • PDB 2C9T
  • Chain 'R':
    Compound: alpha-conotoxin imi
    Species: CONUS IMPERIALIS [TaxId:35631]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50983 (0-11)
    • PDB 2C9T
  • Chain 'S':
    Compound: alpha-conotoxin imi
    Species: CONUS IMPERIALIS [TaxId:35631]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50983 (0-11)
    • PDB 2C9T
  • Chain 'T':
    Compound: alpha-conotoxin imi
    Species: CONUS IMPERIALIS [TaxId:35631]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50983 (0-11)
    • PDB 2C9T
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2c9tA (A:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragngffrnlfd

    Sequence, based on observed residues (ATOM records): (download) 
    >2c9tA (A:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrer

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2c9tB (B:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragngffrnlfd

    Sequence, based on observed residues (ATOM records): (download) 
    >2c9tB (B:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrer

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2c9tC (C:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragngffrnlfd

    Sequence, based on observed residues (ATOM records): (download) 
    >2c9tC (C:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrer

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2c9tD (D:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragngffrnlfd

    Sequence, based on observed residues (ATOM records): (download) 
    >2c9tD (D:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrer

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2c9tE (E:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragngffrnlfd

    Sequence, based on observed residues (ATOM records): (download) 
    >2c9tE (E:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrer

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2c9tF (F:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragngffrnlfd

    Sequence, based on observed residues (ATOM records): (download) 
    >2c9tF (F:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrer

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2c9tG (G:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragngffrnlfd

    Sequence, based on observed residues (ATOM records): (download) 
    >2c9tG (G:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrer

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2c9tH (H:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragngffrnlfd

    Sequence, based on observed residues (ATOM records): (download) 
    >2c9tH (H:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrer

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >2c9tI (I:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragngffrnlfd

    Sequence, based on observed residues (ATOM records): (download) 
    >2c9tI (I:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrer

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >2c9tJ (J:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragngffrnlfd

    Sequence, based on observed residues (ATOM records): (download) 
    >2c9tJ (J:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrer

  • Chain 'K':
    No sequence available.

  • Chain 'M':
    No sequence available.

  • Chain 'O':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'Q':
    No sequence available.

  • Chain 'R':
    No sequence available.

  • Chain 'S':
    No sequence available.

  • Chain 'T':
    No sequence available.