PDB entry 2c91

View 2c91 on RCSB PDB site
Description: mouse succinic semialdehyde reductase, akr7a5
Class: oxidoreductase
Keywords: aldo/keto reductase, akr, succinic semialdehyde reductase, tartrate, golgi stack, nad, nadp, oxidoreductase
Deposited on 2005-12-08, released 2006-02-15
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-31.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.162
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: aflatoxin b1 aldehyde reductase member 2
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8CG76 (Start-337)
      • conflict (97)
      • conflict (132)
    Domains in SCOPe 2.06: d2c91a_
  • Chain 'B':
    Compound: aflatoxin b1 aldehyde reductase member 2
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8CG76 (Start-337)
      • conflict (97)
      • conflict (132)
    Domains in SCOPe 2.06: d2c91b_
  • Chain 'C':
    Compound: aflatoxin b1 aldehyde reductase member 2
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8CG76 (Start-337)
      • conflict (97)
      • conflict (132)
    Domains in SCOPe 2.06: d2c91c_
  • Chain 'D':
    Compound: aflatoxin b1 aldehyde reductase member 2
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8CG76 (Start-337)
      • conflict (97)
      • conflict (132)
    Domains in SCOPe 2.06: d2c91d_
  • Chain 'E':
    Compound: aflatoxin b1 aldehyde reductase member 2
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8CG76 (Start-337)
      • conflict (97)
      • conflict (132)
    Domains in SCOPe 2.06: d2c91e_
  • Chain 'F':
    Compound: aflatoxin b1 aldehyde reductase member 2
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8CG76 (Start-337)
      • conflict (97)
      • conflict (132)
    Domains in SCOPe 2.06: d2c91f_
  • Chain 'G':
    Compound: aflatoxin b1 aldehyde reductase member 2
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8CG76 (Start-337)
      • conflict (97)
      • conflict (132)
    Domains in SCOPe 2.06: d2c91g_
  • Chain 'H':
    Compound: aflatoxin b1 aldehyde reductase member 2
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8CG76 (Start-337)
      • conflict (97)
      • conflict (132)
    Domains in SCOPe 2.06: d2c91h_
  • Chain 'I':
    Compound: aflatoxin b1 aldehyde reductase member 2
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8CG76 (Start-337)
      • conflict (97)
      • conflict (132)
    Domains in SCOPe 2.06: d2c91i_
  • Chain 'J':
    Compound: aflatoxin b1 aldehyde reductase member 2
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8CG76 (Start-337)
      • conflict (97)
      • conflict (132)
    Domains in SCOPe 2.06: d2c91j_
  • Heterogens: NAP, TLA, GOL, PO4, MES, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2c91A (A:)
msrppppraasgaplrpatvlgtmemgrrmdasasaasvraflerghseldtafmycdgq
senilgglglglgsgdctvkiatkanpwegkslkpdsirsqletslkrlqcprvdlfylh
apdhstpveetlcachqlhqegkfvelglsnyaswevaeictlcksngwilptvyqgmyn
attrqveaellpclrhfglrfyaynplagglltgkykyedkdgkqpvgrffgnnwaetyr
nrfwkehhfeaialvekalqttygtnaprmtsaalrwmyhhsqlqgtrgdavilgmssle
qleqnlaateegplepavveafdqawnmvahecpnyfr

    Sequence, based on observed residues (ATOM records): (download) 
    >2c91A (A:)
plrpatvlgtmemgrrmdasasaasvraflerghseldtafmycdgqsenilgglglglg
sgdctvkiatkanpwegkslkpdsirsqletslkrlqcprvdlfylhapdhstpveetlc
achqlhqegkfvelglsnyaswevaeictlcksngwilptvyqgmynattrqveaellpc
lrhfglrfyaynplagglltgkykyedkdgkqpvgrffgnnwaetyrnrfwkehhfeaia
lvekalqttygtnaprmtsaalrwmyhhsqlqgtrgdavilgmssleqleqnlaateegp
lepavveafdqawnmvahecpnyfr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2c91B (B:)
msrppppraasgaplrpatvlgtmemgrrmdasasaasvraflerghseldtafmycdgq
senilgglglglgsgdctvkiatkanpwegkslkpdsirsqletslkrlqcprvdlfylh
apdhstpveetlcachqlhqegkfvelglsnyaswevaeictlcksngwilptvyqgmyn
attrqveaellpclrhfglrfyaynplagglltgkykyedkdgkqpvgrffgnnwaetyr
nrfwkehhfeaialvekalqttygtnaprmtsaalrwmyhhsqlqgtrgdavilgmssle
qleqnlaateegplepavveafdqawnmvahecpnyfr

    Sequence, based on observed residues (ATOM records): (download) 
    >2c91B (B:)
lrpatvlgtmemgrrmdasasaasvraflerghseldtafmycdgqsenilgglglglgs
gdctvkiatkanpwegkslkpdsirsqletslkrlqcprvdlfylhapdhstpveetlca
chqlhqegkfvelglsnyaswevaeictlcksngwilptvyqgmynattrqveaellpcl
rhfglrfyaynplagglltgkykyedkdgkqpvgrffgnnwaetyrnrfwkehhfeaial
vekalqttygtnaprmtsaalrwmyhhsqlqgtrgdavilgmssleqleqnlaateegpl
epavveafdqawnmvahecpnyfr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2c91C (C:)
msrppppraasgaplrpatvlgtmemgrrmdasasaasvraflerghseldtafmycdgq
senilgglglglgsgdctvkiatkanpwegkslkpdsirsqletslkrlqcprvdlfylh
apdhstpveetlcachqlhqegkfvelglsnyaswevaeictlcksngwilptvyqgmyn
attrqveaellpclrhfglrfyaynplagglltgkykyedkdgkqpvgrffgnnwaetyr
nrfwkehhfeaialvekalqttygtnaprmtsaalrwmyhhsqlqgtrgdavilgmssle
qleqnlaateegplepavveafdqawnmvahecpnyfr

    Sequence, based on observed residues (ATOM records): (download) 
    >2c91C (C:)
lrpatvlgtmemgrrmdasasaasvraflerghseldtafmycdgqsenilgglglglgs
gdctvkiatkanpwegkslkpdsirsqletslkrlqcprvdlfylhapdhstpveetlca
chqlhqegkfvelglsnyaswevaeictlcksngwilptvyqgmynattrqveaellpcl
rhfglrfyaynplagglltgkykyedkdgkqpvgrffgnnwaetyrnrfwkehhfeaial
vekalqttygtnaprmtsaalrwmyhhsqlqgtrgdavilgmssleqleqnlaateegpl
epavveafdqawnmvahecpnyfr

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2c91D (D:)
msrppppraasgaplrpatvlgtmemgrrmdasasaasvraflerghseldtafmycdgq
senilgglglglgsgdctvkiatkanpwegkslkpdsirsqletslkrlqcprvdlfylh
apdhstpveetlcachqlhqegkfvelglsnyaswevaeictlcksngwilptvyqgmyn
attrqveaellpclrhfglrfyaynplagglltgkykyedkdgkqpvgrffgnnwaetyr
nrfwkehhfeaialvekalqttygtnaprmtsaalrwmyhhsqlqgtrgdavilgmssle
qleqnlaateegplepavveafdqawnmvahecpnyfr

    Sequence, based on observed residues (ATOM records): (download) 
    >2c91D (D:)
lrpatvlgtmemgrrmdasasaasvraflerghseldtafmycdgqsenilgglglglgs
gdctvkiatkanpwegkslkpdsirsqletslkrlqcprvdlfylhapdhstpveetlca
chqlhqegkfvelglsnyaswevaeictlcksngwilptvyqgmynattrqveaellpcl
rhfglrfyaynplagglltgkykyedkdgkqpvgrffgnnwaetyrnrfwkehhfeaial
vekalqttygtnaprmtsaalrwmyhhsqlqgtrgdavilgmssleqleqnlaateegpl
epavveafdqawnmvahecpnyfr

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2c91E (E:)
msrppppraasgaplrpatvlgtmemgrrmdasasaasvraflerghseldtafmycdgq
senilgglglglgsgdctvkiatkanpwegkslkpdsirsqletslkrlqcprvdlfylh
apdhstpveetlcachqlhqegkfvelglsnyaswevaeictlcksngwilptvyqgmyn
attrqveaellpclrhfglrfyaynplagglltgkykyedkdgkqpvgrffgnnwaetyr
nrfwkehhfeaialvekalqttygtnaprmtsaalrwmyhhsqlqgtrgdavilgmssle
qleqnlaateegplepavveafdqawnmvahecpnyfr

    Sequence, based on observed residues (ATOM records): (download) 
    >2c91E (E:)
lrpatvlgtmemgrrmdasasaasvraflerghseldtafmycdgqsenilgglglglgs
gdctvkiatkanpwegkslkpdsirsqletslkrlqcprvdlfylhapdhstpveetlca
chqlhqegkfvelglsnyaswevaeictlcksngwilptvyqgmynattrqveaellpcl
rhfglrfyaynplagglltgkykyedkdgkqpvgrffgnnwaetyrnrfwkehhfeaial
vekalqttygtnaprmtsaalrwmyhhsqlqgtrgdavilgmssleqleqnlaateegpl
epavveafdqawnmvahecpnyfr

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2c91F (F:)
msrppppraasgaplrpatvlgtmemgrrmdasasaasvraflerghseldtafmycdgq
senilgglglglgsgdctvkiatkanpwegkslkpdsirsqletslkrlqcprvdlfylh
apdhstpveetlcachqlhqegkfvelglsnyaswevaeictlcksngwilptvyqgmyn
attrqveaellpclrhfglrfyaynplagglltgkykyedkdgkqpvgrffgnnwaetyr
nrfwkehhfeaialvekalqttygtnaprmtsaalrwmyhhsqlqgtrgdavilgmssle
qleqnlaateegplepavveafdqawnmvahecpnyfr

    Sequence, based on observed residues (ATOM records): (download) 
    >2c91F (F:)
lrpatvlgtmemgrrmdasasaasvraflerghseldtafmycdgqsenilgglglglgs
gdctvkiatkanpwegkslkpdsirsqletslkrlqcprvdlfylhapdhstpveetlca
chqlhqegkfvelglsnyaswevaeictlcksngwilptvyqgmynattrqveaellpcl
rhfglrfyaynplagglltgkykyedkdgkqpvgrffgnnwaetyrnrfwkehhfeaial
vekalqttygtnaprmtsaalrwmyhhsqlqgtrgdavilgmssleqleqnlaateegpl
epavveafdqawnmvahecpnyfr

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2c91G (G:)
msrppppraasgaplrpatvlgtmemgrrmdasasaasvraflerghseldtafmycdgq
senilgglglglgsgdctvkiatkanpwegkslkpdsirsqletslkrlqcprvdlfylh
apdhstpveetlcachqlhqegkfvelglsnyaswevaeictlcksngwilptvyqgmyn
attrqveaellpclrhfglrfyaynplagglltgkykyedkdgkqpvgrffgnnwaetyr
nrfwkehhfeaialvekalqttygtnaprmtsaalrwmyhhsqlqgtrgdavilgmssle
qleqnlaateegplepavveafdqawnmvahecpnyfr

    Sequence, based on observed residues (ATOM records): (download) 
    >2c91G (G:)
lrpatvlgtmemgrrmdasasaasvraflerghseldtafmycdgqsenilgglglglgs
gdctvkiatkanpwegkslkpdsirsqletslkrlqcprvdlfylhapdhstpveetlca
chqlhqegkfvelglsnyaswevaeictlcksngwilptvyqgmynattrqveaellpcl
rhfglrfyaynplagglltgkykyedkdgkqpvgrffgnnwaetyrnrfwkehhfeaial
vekalqttygtnaprmtsaalrwmyhhsqlqgtrgdavilgmssleqleqnlaateegpl
epavveafdqawnmvahecpnyfr

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2c91H (H:)
msrppppraasgaplrpatvlgtmemgrrmdasasaasvraflerghseldtafmycdgq
senilgglglglgsgdctvkiatkanpwegkslkpdsirsqletslkrlqcprvdlfylh
apdhstpveetlcachqlhqegkfvelglsnyaswevaeictlcksngwilptvyqgmyn
attrqveaellpclrhfglrfyaynplagglltgkykyedkdgkqpvgrffgnnwaetyr
nrfwkehhfeaialvekalqttygtnaprmtsaalrwmyhhsqlqgtrgdavilgmssle
qleqnlaateegplepavveafdqawnmvahecpnyfr

    Sequence, based on observed residues (ATOM records): (download) 
    >2c91H (H:)
lrpatvlgtmemgrrmdasasaasvraflerghseldtafmycdgqsenilgglglglgs
gdctvkiatkanpwegkslkpdsirsqletslkrlqcprvdlfylhapdhstpveetlca
chqlhqegkfvelglsnyaswevaeictlcksngwilptvyqgmynattrqveaellpcl
rhfglrfyaynplagglltgkykyedkdgkqpvgrffgnnwaetyrnrfwkehhfeaial
vekalqttygtnaprmtsaalrwmyhhsqlqgtrgdavilgmssleqleqnlaateegpl
epavveafdqawnmvahecpnyfr

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >2c91I (I:)
msrppppraasgaplrpatvlgtmemgrrmdasasaasvraflerghseldtafmycdgq
senilgglglglgsgdctvkiatkanpwegkslkpdsirsqletslkrlqcprvdlfylh
apdhstpveetlcachqlhqegkfvelglsnyaswevaeictlcksngwilptvyqgmyn
attrqveaellpclrhfglrfyaynplagglltgkykyedkdgkqpvgrffgnnwaetyr
nrfwkehhfeaialvekalqttygtnaprmtsaalrwmyhhsqlqgtrgdavilgmssle
qleqnlaateegplepavveafdqawnmvahecpnyfr

    Sequence, based on observed residues (ATOM records): (download) 
    >2c91I (I:)
lrpatvlgtmemgrrmdasasaasvraflerghseldtafmycdgqsenilgglglglgs
gdctvkiatkanpwegkslkpdsirsqletslkrlqcprvdlfylhapdhstpveetlca
chqlhqegkfvelglsnyaswevaeictlcksngwilptvyqgmynattrqveaellpcl
rhfglrfyaynplagglltgkykyedkdgkqpvgrffgnnwaetyrnrfwkehhfeaial
vekalqttygtnaprmtsaalrwmyhhsqlqgtrgdavilgmssleqleqnlaateegpl
epavveafdqawnmvahecpnyfr

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >2c91J (J:)
msrppppraasgaplrpatvlgtmemgrrmdasasaasvraflerghseldtafmycdgq
senilgglglglgsgdctvkiatkanpwegkslkpdsirsqletslkrlqcprvdlfylh
apdhstpveetlcachqlhqegkfvelglsnyaswevaeictlcksngwilptvyqgmyn
attrqveaellpclrhfglrfyaynplagglltgkykyedkdgkqpvgrffgnnwaetyr
nrfwkehhfeaialvekalqttygtnaprmtsaalrwmyhhsqlqgtrgdavilgmssle
qleqnlaateegplepavveafdqawnmvahecpnyfr

    Sequence, based on observed residues (ATOM records): (download) 
    >2c91J (J:)
plrpatvlgtmemgrrmdasasaasvraflerghseldtafmycdgqsenilgglglglg
sgdctvkiatkanpwegkslkpdsirsqletslkrlqcprvdlfylhapdhstpveetlc
achqlhqegkfvelglsnyaswevaeictlcksngwilptvyqgmynattrqveaellpc
lrhfglrfyaynplagglltgkykyedkdgkqpvgrffgnnwaetyrnrfwkehhfeaia
lvekalqttygtnaprmtsaalrwmyhhsqlqgtrgdavilgmssleqleqnlaateegp
lepavveafdqawnmvahecpnyfr