PDB entry 2c8u

View 2c8u on RCSB PDB site
Description: structure of r21q mutant of sh28gst
Class: transferase
Keywords: sigma class gst, detoxification, glutathione, prostaglandin d2 synthase, mutant, transferase
Deposited on 2005-12-07, released 2006-06-21
The last revision prior to the SCOP 1.73 freeze date was dated 2006-07-12, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.22762
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glutathione s-transferase 28 kda
    Species: Schistosoma haematobium
    Database cross-references and differences (RAF-indexed):
    • Uniprot P30113
      • engineered mutation (20)
    Domains in SCOP 1.73: d2c8ua1, d2c8ua2
  • Chain 'B':
    Compound: glutathione s-transferase 28 kda
    Species: Schistosoma haematobium
    Database cross-references and differences (RAF-indexed):
    • Uniprot P30113
      • engineered mutation (20)
    Domains in SCOP 1.73: d2c8ub1, d2c8ub2
  • Heterogens: SO4, BME, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2c8uA (A:)
mtgdhikviyfngrgraesiqmtlvaagvnyederisfqdwpkikptipggrlpavkitd
nhghvkwmveslaiarymakkhhmmggteeeyynvekligqaedleheyyktlmkpeeek
qkiikeilngkvpvlldiiceslkastgklavgdkvtladlvliavidhvtdldkefltg
kypeihkhrenllassprlakylsdraatpf

    Sequence, based on observed residues (ATOM records): (download) 
    >2c8uA (A:)
dhikviyfngrgraesiqmtlvaagvnyederisfqdwpkikptipggrlpavkitdnhg
hvkwmveslaiarymakkhhmmggteeeyynvekligqaedleheyyktlmkpeeekqki
ikeilngkvpvlldiiceslkastgklavgdkvtladlvliavidhvtdldkefltgkyp
eihkhrenllassprlakylsd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2c8uB (B:)
mtgdhikviyfngrgraesiqmtlvaagvnyederisfqdwpkikptipggrlpavkitd
nhghvkwmveslaiarymakkhhmmggteeeyynvekligqaedleheyyktlmkpeeek
qkiikeilngkvpvlldiiceslkastgklavgdkvtladlvliavidhvtdldkefltg
kypeihkhrenllassprlakylsdraatpf

    Sequence, based on observed residues (ATOM records): (download) 
    >2c8uB (B:)
dhikviyfngrgraesiqmtlvaagvnyederisfqdwpkikptipggrlpavkitdnhg
hvkwmveslaiarymakkhhmmggteeeyynvekligqaedleheyyktlmkpeeekqki
ikeilngkvpvlldiiceslkastgklavgdkvtladlvliavidhvtdldkefltgkyp
eihkhrenllassprlakylsd