PDB entry 2c8u

View 2c8u on RCSB PDB site
Description: Structure of R21Q mutant of Sh28GST
Class: transferase
Keywords: sigma class gst, detoxification, glutathione, prostaglandin d2 synthase, mutant, transferase
Deposited on 2005-12-07, released 2006-06-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-05-08, with a file datestamp of 2013-05-03.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.228
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glutathione s-transferase 28 kda
    Species: SCHISTOSOMA HAEMATOBIUM [TaxId:6185]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P30113
      • engineered mutation (20)
    Domains in SCOPe 2.08: d2c8ua1, d2c8ua2
  • Chain 'B':
    Compound: glutathione s-transferase 28 kda
    Species: SCHISTOSOMA HAEMATOBIUM [TaxId:6185]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P30113
      • engineered mutation (20)
    Domains in SCOPe 2.08: d2c8ub1, d2c8ub2
  • Heterogens: SO4, BME, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2c8uA (A:)
mtgdhikviyfngrgraesiqmtlvaagvnyederisfqdwpkikptipggrlpavkitd
nhghvkwmveslaiarymakkhhmmggteeeyynvekligqaedleheyyktlmkpeeek
qkiikeilngkvpvlldiiceslkastgklavgdkvtladlvliavidhvtdldkefltg
kypeihkhrenllassprlakylsdraatpf

    Sequence, based on observed residues (ATOM records): (download) 
    >2c8uA (A:)
dhikviyfngrgraesiqmtlvaagvnyederisfqdwpkikptipggrlpavkitdnhg
hvkwmveslaiarymakkhhmmggteeeyynvekligqaedleheyyktlmkpeeekqki
ikeilngkvpvlldiiceslkastgklavgdkvtladlvliavidhvtdldkefltgkyp
eihkhrenllassprlakylsd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2c8uB (B:)
mtgdhikviyfngrgraesiqmtlvaagvnyederisfqdwpkikptipggrlpavkitd
nhghvkwmveslaiarymakkhhmmggteeeyynvekligqaedleheyyktlmkpeeek
qkiikeilngkvpvlldiiceslkastgklavgdkvtladlvliavidhvtdldkefltg
kypeihkhrenllassprlakylsdraatpf

    Sequence, based on observed residues (ATOM records): (download) 
    >2c8uB (B:)
dhikviyfngrgraesiqmtlvaagvnyederisfqdwpkikptipggrlpavkitdnhg
hvkwmveslaiarymakkhhmmggteeeyynvekligqaedleheyyktlmkpeeekqki
ikeilngkvpvlldiiceslkastgklavgdkvtladlvliavidhvtdldkefltgkyp
eihkhrenllassprlakylsd