PDB entry 2c8t

View 2c8t on RCSB PDB site
Description: the 3.0 a resolution structure of caseinolytic clp protease 1 from mycobacterium tuberculosis
Class: hydrolase
Keywords: serine protease, clpp1, hydrolase
Deposited on 2005-12-07, released 2007-02-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-31.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.214
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ATP-dependent clp protease proteolytic subunit 1
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c8ta_
  • Chain 'B':
    Compound: ATP-dependent clp protease proteolytic subunit 1
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c8tb_
  • Chain 'C':
    Compound: ATP-dependent clp protease proteolytic subunit 1
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c8tc_
  • Chain 'D':
    Compound: ATP-dependent clp protease proteolytic subunit 1
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c8td_
  • Chain 'E':
    Compound: ATP-dependent clp protease proteolytic subunit 1
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c8te_
  • Chain 'F':
    Compound: ATP-dependent clp protease proteolytic subunit 1
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c8tf_
  • Chain 'G':
    Compound: ATP-dependent clp protease proteolytic subunit 1
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c8tg_
  • Chain 'H':
    Compound: ATP-dependent clp protease proteolytic subunit 1
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c8th_
  • Chain 'I':
    Compound: ATP-dependent clp protease proteolytic subunit 1
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c8ti_
  • Chain 'J':
    Compound: ATP-dependent clp protease proteolytic subunit 1
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c8tj_
  • Chain 'K':
    Compound: ATP-dependent clp protease proteolytic subunit 1
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c8tk_
  • Chain 'L':
    Compound: ATP-dependent clp protease proteolytic subunit 1
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c8tl_
  • Chain 'M':
    Compound: ATP-dependent clp protease proteolytic subunit 1
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c8tm_
  • Chain 'N':
    Compound: ATP-dependent clp protease proteolytic subunit 1
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c8tn_

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2c8tA (A:)
masqvtdmrsnsqglsltdsvyerllseriiflgsevndeianrlcaqilllaaedaskd
islyinspggsisagmaiydtmvlapcdiatyamgmaasmgefllaagtkgkryalphar
ilmhqplggvtgsaadiaiqaeqfavikkemfrlnaeftgqpierieadsdrdrwftaae
aleygfvdhiitrahvngeaqghhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2c8tA (A:)
sltdsvyerllseriiflgsevndeianrlcaqilllaaedaskdislyinspggsisag
maiydtmvlapcdiatyamgmaasmgefllaagtkgkryalpharilmhqpliaiqaeqf
avikkemfrlnaeftgqpierieadsdrdrwftaaealeygfvdhiitrah

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2c8tB (B:)
masqvtdmrsnsqglsltdsvyerllseriiflgsevndeianrlcaqilllaaedaskd
islyinspggsisagmaiydtmvlapcdiatyamgmaasmgefllaagtkgkryalphar
ilmhqplggvtgsaadiaiqaeqfavikkemfrlnaeftgqpierieadsdrdrwftaae
aleygfvdhiitrahvngeaqghhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2c8tB (B:)
sltdsvyerllseriiflgsevndeianrlcaqilllaaedaskdislyinspggsisag
maiydtmvlapcdiatyamgmaasmgefllaagtkgkryalpharilmhqpliaiqaeqf
avikkemfrlnaeftgqpierieadsdrdrwftaaealeygfvdhiitrah

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2c8tC (C:)
masqvtdmrsnsqglsltdsvyerllseriiflgsevndeianrlcaqilllaaedaskd
islyinspggsisagmaiydtmvlapcdiatyamgmaasmgefllaagtkgkryalphar
ilmhqplggvtgsaadiaiqaeqfavikkemfrlnaeftgqpierieadsdrdrwftaae
aleygfvdhiitrahvngeaqghhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2c8tC (C:)
sltdsvyerllseriiflgsevndeianrlcaqilllaaedaskdislyinspggsisag
maiydtmvlapcdiatyamgmaasmgefllaagtkgkryalpharilmhqpliaiqaeqf
avikkemfrlnaeftgqpierieadsdrdrwftaaealeygfvdhiitrah

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2c8tD (D:)
masqvtdmrsnsqglsltdsvyerllseriiflgsevndeianrlcaqilllaaedaskd
islyinspggsisagmaiydtmvlapcdiatyamgmaasmgefllaagtkgkryalphar
ilmhqplggvtgsaadiaiqaeqfavikkemfrlnaeftgqpierieadsdrdrwftaae
aleygfvdhiitrahvngeaqghhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2c8tD (D:)
sltdsvyerllseriiflgsevndeianrlcaqilllaaedaskdislyinspggsisag
maiydtmvlapcdiatyamgmaasmgefllaagtkgkryalpharilmhqpliaiqaeqf
avikkemfrlnaeftgqpierieadsdrdrwftaaealeygfvdhiitrah

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2c8tE (E:)
masqvtdmrsnsqglsltdsvyerllseriiflgsevndeianrlcaqilllaaedaskd
islyinspggsisagmaiydtmvlapcdiatyamgmaasmgefllaagtkgkryalphar
ilmhqplggvtgsaadiaiqaeqfavikkemfrlnaeftgqpierieadsdrdrwftaae
aleygfvdhiitrahvngeaqghhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2c8tE (E:)
sltdsvyerllseriiflgsevndeianrlcaqilllaaedaskdislyinspggsisag
maiydtmvlapcdiatyamgmaasmgefllaagtkgkryalpharilmhqpliaiqaeqf
avikkemfrlnaeftgqpierieadsdrdrwftaaealeygfvdhiitrah

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2c8tF (F:)
masqvtdmrsnsqglsltdsvyerllseriiflgsevndeianrlcaqilllaaedaskd
islyinspggsisagmaiydtmvlapcdiatyamgmaasmgefllaagtkgkryalphar
ilmhqplggvtgsaadiaiqaeqfavikkemfrlnaeftgqpierieadsdrdrwftaae
aleygfvdhiitrahvngeaqghhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2c8tF (F:)
sltdsvyerllseriiflgsevndeianrlcaqilllaaedaskdislyinspggsisag
maiydtmvlapcdiatyamgmaasmgefllaagtkgkryalpharilmhqpliaiqaeqf
avikkemfrlnaeftgqpierieadsdrdrwftaaealeygfvdhiitrah

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2c8tG (G:)
masqvtdmrsnsqglsltdsvyerllseriiflgsevndeianrlcaqilllaaedaskd
islyinspggsisagmaiydtmvlapcdiatyamgmaasmgefllaagtkgkryalphar
ilmhqplggvtgsaadiaiqaeqfavikkemfrlnaeftgqpierieadsdrdrwftaae
aleygfvdhiitrahvngeaqghhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2c8tG (G:)
sltdsvyerllseriiflgsevndeianrlcaqilllaaedaskdislyinspggsisag
maiydtmvlapcdiatyamgmaasmgefllaagtkgkryalpharilmhqpliaiqaeqf
avikkemfrlnaeftgqpierieadsdrdrwftaaealeygfvdhiitrah

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2c8tH (H:)
masqvtdmrsnsqglsltdsvyerllseriiflgsevndeianrlcaqilllaaedaskd
islyinspggsisagmaiydtmvlapcdiatyamgmaasmgefllaagtkgkryalphar
ilmhqplggvtgsaadiaiqaeqfavikkemfrlnaeftgqpierieadsdrdrwftaae
aleygfvdhiitrahvngeaqghhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2c8tH (H:)
sltdsvyerllseriiflgsevndeianrlcaqilllaaedaskdislyinspggsisag
maiydtmvlapcdiatyamgmaasmgefllaagtkgkryalpharilmhqpliaiqaeqf
avikkemfrlnaeftgqpierieadsdrdrwftaaealeygfvdhiitrah

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >2c8tI (I:)
masqvtdmrsnsqglsltdsvyerllseriiflgsevndeianrlcaqilllaaedaskd
islyinspggsisagmaiydtmvlapcdiatyamgmaasmgefllaagtkgkryalphar
ilmhqplggvtgsaadiaiqaeqfavikkemfrlnaeftgqpierieadsdrdrwftaae
aleygfvdhiitrahvngeaqghhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2c8tI (I:)
sltdsvyerllseriiflgsevndeianrlcaqilllaaedaskdislyinspggsisag
maiydtmvlapcdiatyamgmaasmgefllaagtkgkryalpharilmhqpliaiqaeqf
avikkemfrlnaeftgqpierieadsdrdrwftaaealeygfvdhiitrah

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >2c8tJ (J:)
masqvtdmrsnsqglsltdsvyerllseriiflgsevndeianrlcaqilllaaedaskd
islyinspggsisagmaiydtmvlapcdiatyamgmaasmgefllaagtkgkryalphar
ilmhqplggvtgsaadiaiqaeqfavikkemfrlnaeftgqpierieadsdrdrwftaae
aleygfvdhiitrahvngeaqghhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2c8tJ (J:)
sltdsvyerllseriiflgsevndeianrlcaqilllaaedaskdislyinspggsisag
maiydtmvlapcdiatyamgmaasmgefllaagtkgkryalpharilmhqpliaiqaeqf
avikkemfrlnaeftgqpierieadsdrdrwftaaealeygfvdhiitrah

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >2c8tK (K:)
masqvtdmrsnsqglsltdsvyerllseriiflgsevndeianrlcaqilllaaedaskd
islyinspggsisagmaiydtmvlapcdiatyamgmaasmgefllaagtkgkryalphar
ilmhqplggvtgsaadiaiqaeqfavikkemfrlnaeftgqpierieadsdrdrwftaae
aleygfvdhiitrahvngeaqghhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2c8tK (K:)
sltdsvyerllseriiflgsevndeianrlcaqilllaaedaskdislyinspggsisag
maiydtmvlapcdiatyamgmaasmgefllaagtkgkryalpharilmhqpliaiqaeqf
avikkemfrlnaeftgqpierieadsdrdrwftaaealeygfvdhiitrah

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >2c8tL (L:)
masqvtdmrsnsqglsltdsvyerllseriiflgsevndeianrlcaqilllaaedaskd
islyinspggsisagmaiydtmvlapcdiatyamgmaasmgefllaagtkgkryalphar
ilmhqplggvtgsaadiaiqaeqfavikkemfrlnaeftgqpierieadsdrdrwftaae
aleygfvdhiitrahvngeaqghhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2c8tL (L:)
sltdsvyerllseriiflgsevndeianrlcaqilllaaedaskdislyinspggsisag
maiydtmvlapcdiatyamgmaasmgefllaagtkgkryalpharilmhqpliaiqaeqf
avikkemfrlnaeftgqpierieadsdrdrwftaaealeygfvdhiitrah

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >2c8tM (M:)
masqvtdmrsnsqglsltdsvyerllseriiflgsevndeianrlcaqilllaaedaskd
islyinspggsisagmaiydtmvlapcdiatyamgmaasmgefllaagtkgkryalphar
ilmhqplggvtgsaadiaiqaeqfavikkemfrlnaeftgqpierieadsdrdrwftaae
aleygfvdhiitrahvngeaqghhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2c8tM (M:)
sltdsvyerllseriiflgsevndeianrlcaqilllaaedaskdislyinspggsisag
maiydtmvlapcdiatyamgmaasmgefllaagtkgkryalpharilmhqpliaiqaeqf
avikkemfrlnaeftgqpierieadsdrdrwftaaealeygfvdhiitrah

  • Chain 'N':
    Sequence, based on SEQRES records: (download) 
    >2c8tN (N:)
masqvtdmrsnsqglsltdsvyerllseriiflgsevndeianrlcaqilllaaedaskd
islyinspggsisagmaiydtmvlapcdiatyamgmaasmgefllaagtkgkryalphar
ilmhqplggvtgsaadiaiqaeqfavikkemfrlnaeftgqpierieadsdrdrwftaae
aleygfvdhiitrahvngeaqghhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2c8tN (N:)
sltdsvyerllseriiflgsevndeianrlcaqilllaaedaskdislyinspggsisag
maiydtmvlapcdiatyamgmaasmgefllaagtkgkryalpharilmhqpliaiqaeqf
avikkemfrlnaeftgqpierieadsdrdrwftaaealeygfvdhiitrah