PDB entry 2c8i

View 2c8i on RCSB PDB site
Description: complex of echovirus type 12 with domains 1, 2, 3 and 4 of its receptor decay accelerating factor (cd55) by cryo electron microscopy at 16 a
Class: Virus/Receptor
Keywords: ECHOVIRUS, PICORNAVIRUS, CD55, DAF, VIRUS-RECEPTOR COMPLEX, ANTIGEN, BLOOD GROUP ANTIGEN, COMPLEMENT PATHWAY, GLYCOPROTEIN, GPI-ANCHOR, IMMUNE RESPONSE, INNATE IMMUNITY, LIPOPROTEIN, PLASMA, POLYMORPHISM, SUSHI, COMPLEX (VIRUS COAT/IMMUNE PROTEIN), Icosahedral virus
Deposited on 2005-12-05, released 2006-01-17
The last revision prior to the SCOP 1.73 freeze date was dated 2006-02-22, with a file datestamp of 2007-06-04.
Experiment type: EM
Resolution: 16 Å
R-factor: N/A
AEROSPACI score: -0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: echovirus 11 coat protein vp1
    Species: Human echovirus 11
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2c8ia1
  • Chain 'B':
    Compound: echovirus 11 coat protein vp2
    Species: Human echovirus 11
    Database cross-references and differences (RAF-indexed):
    • Uniprot P29813 (0-251)
      • conflict (216)
  • Chain 'C':
    Compound: echovirus 11 coat protein vp3
    Species: Human echovirus 11
    Database cross-references and differences (RAF-indexed):
    • Uniprot P29813 (0-237)
      • conflict (62)
    Domains in SCOP 1.73: d2c8ic1
  • Chain 'D':
    Compound: echovirus 11 coat protein vp4
    Species: Human echovirus 11
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: complement decay-accelerating factor
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2c8ie1, d2c8ie2, d2c8ie3, d2c8ie4

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2c8iA (A:)
gdvveavenavarvadtigsgpsnsqavpaltavetghtsqvtpsdtvqtrhvknyhsrs
essienflsrsacvymgeyhttnsdqtklfaswtisarrmvqmrrkleiftyvrfdvevt
fvitskqdqgtqlgqdmpplthqimyippggpipksvtdytwqtstnpsifwtegnappr
msipfisignaysnfydgwshfsqngvygyntlnhmgqiyvrhvngssplpmtstvrmyf
kpkhvkawvprpprlcqyknastvnfsptditdkrnsityipdtvkpdv

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2c8iC (C:)
glpvintpgsnqfltsddfqspsampqfdvtpelnipgevqnlmeiaevdsvvpvnnvag
nletmdiyripvqsgnhqssqvfgfqvqpgldgvfkhtllgeilnyyahwsgsikltfvf
cgsamatgkfllayappganapksrkdamlgthiiwdvglqsscvlcipwisqthyrlvq
qdeytsagnvtcwyqtgivvpagtptscsimcfvsacndfsvrllkdtpfiqqaallq

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2c8iE (E:)
qdcglppdvpnaqpalegrtsfpedtvitykceesfvkipgekdsviclkgsqwsdieef
cnrsqdcglppdvpnaqpalegrtsfpedtvitykceesfvkipgekdsviclkgsqwsd
ieefcnrscevptrlnsaslkqpyitqnyfpvgtvveyecrpgyrrepslspkltclqnl
kwstavefckkkscpnpgeirngqidvpggilfgatisfscntgyklfgstssfclisgs
svqwsdplpecreiycpappqidngiiqgerdhygyrqsvtyacnkgftmigehsiyctv
nndegewsgpppecrg

    Sequence, based on observed residues (ATOM records): (download) 
    >2c8iE (E:)
qdcglppdvpnaqpalegrtsfpedtvitykceesfvkipgekdsviclkgsqwsdieef
cnrscevptrlnsaslkqpyitqnyfpvgtvveyecrpgyrrepslspkltclqnlkwst
avefckkkscpnpgeirngqidvpggilfgatisfscntgyklfgstssfclisgssvqw
sdplpecreiycpappqidngiiqgerdhygyrqsvtyacnkgftmigehsiyctvnnde
gewsgpppecrg