PDB entry 2c77

View 2c77 on RCSB PDB site
Description: EF-Tu complexed with a GTP analog and the antibiotic GE2270 A
Class: hydrolase/antibiotic
Keywords: hydrolase-antibiotic complex, thiopeptide, antibiotic, antibacterial, thiazole, oxazole, hydrolase, gtpase, translation elongation factor, protein synthesis, nucleotide-binding, phosphorylation
Deposited on 2005-11-18, released 2006-03-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-24, with a file datestamp of 2019-07-19.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Elongation factor Tu-B
    Species: Thermus thermophilus [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P60339 (Start-404)
      • conflict (32)
    Domains in SCOPe 2.08: d2c77a1, d2c77a2, d2c77a3
  • Chain 'B':
    Compound: thiocillin ge2270
    Species: PLANOBISPORA ROSEA [TaxId:35762]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: GNP, MG, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2c77A (A:)
akgefirtkphvnvgtighvdhgkttltaaltyvtaaenpnvevkdygdidkapeerarg
itintahveyetakrhyshvdcpghadyiknmitgaaqmdgailvvsaadgpmpqtrehi
llarqvgvpyivvfmnkvdmvddpelldlvemevrdllnqyefpgdevpvirgsallale
qmhrnpktrrgenewvdkiwelldaideyiptpvrdvdkpflmpvedvftitgrgtvatg
riergkvkvgdeveivglapetrktvvtgvemhrktlqegiagdnvgvllrgvsreever
gqvlakpgsitphtkfeasvyvlkkeeggrhtgffsgyrpqfyfrttdvtgvvqlppgve
mvmpgdnvtftvelikpvaleeglrfaireggrtvgagvvtkile

    Sequence, based on observed residues (ATOM records): (download) 
    >2c77A (A:)
kgefirtkphvnvgtighvdhgkttltaaltyvtaaenpnvevkdygdidkapeerargi
tintahveyetakrhyshvdcpghadyiknmitgaaqmdgailvvsaadgpmpqtrehil
larqvgvpyivvfmnkvdmvddpelldlvemevrdllnqyefpgdevpvirgsallaleq
mhrnpktrrgenewvdkiwelldaideyiptpvrdvdkpflmpvedvftitgrgtvatgr
iergkvkvgdeveivglapetrktvvtgvemhrktlqegiagdnvgvllrgvsreeverg
qvlakpgsitphtkfeasvyvlkkeeggrhtgffsgyrpqfyfrttdvtgvvqlppgvem
vmpgdnvtftvelikpvaleeglrfaireggrtvgagvvtkile

  • Chain 'B':
    No sequence available.