PDB entry 2c6p

View 2c6p on RCSB PDB site
Description: Membrane-bound glutamate carboxypeptidase II (GCPII) in complex with phosphate anion
Class: hydrolase
Keywords: naaladase, neurodegenerative disease, peptidase, prostate cancer, psma, glycoprotein, hydrolase, alternative splicing, antigen, carboxypeptidase, dipeptidase, metal-binding, metalloprotease, multifunctional enzyme, polymorphism, signal-anchor, transmembrane, zinc
Deposited on 2005-11-11, released 2006-02-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.39 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glutamate carboxypeptidase II
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c6pa1, d2c6pa2, d2c6pa3
  • Heterogens: ZN, CA, CL, NAG, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2c6pA (A:)
kssneatnitpkhnmkafldelkaenikkflynftqiphlagteqnfqlakqiqsqwkef
gldsvelahydvllsypnkthpnyisiinedgneifntslfeppppgyenvsdivppfsa
fspqgmpegdlvyvnyartedffklerdmkincsgkiviarygkvfrgnkvknaqlagak
gvilysdpadyfapgvksypdgwnlpgggvqrgnilnlngagdpltpgypaneyayrrgi
aeavglpsipvhpigyydaqkllekmggsappdsswrgslkvpynvgpgftgnfstqkvk
mhihstnevtriynvigtlrgavepdryvilgghrdswvfggidpqsgaavvheivrsfg
tlkkegwrprrtilfaswdaeefgllgstewaeensrllqergvayinadssiegnytlr
vdctplmyslvhnltkelkspdegfegkslyeswtkkspspefsgmprisklgsgndfev
ffqrlgiasgrarytknwetnkfsgyplyhsvyetyelvekfydpmfkyhltvaqvrggm
vfelansivlpfdcrdyavvlrkyadkiysismkhpqemktysvsfdslfsavknfteia
skfserlqdfdksnpivlrmmndqlmflerafidplglpdrpfyrhviyapsshnkyage
sfpgiydalfdieskvdpskawgevkrqiyvaaftvqaaaetlseva

    Sequence, based on observed residues (ATOM records): (download) 
    >2c6pA (A:)
nmkafldelkaenikkflynftqiphlagteqnfqlakqiqsqwkefgldsvelahydvl
lsypnkthpnyisiinedgneifntslfeppppgyenvsdivppfsafspqgmpegdlvy
vnyartedffklerdmkincsgkiviarygkvfrgnkvknaqlagakgvilysdpadyfa
pgvksypdgwnlpgggvqrgnilnlngagdpltpgypaneyayrrgiaeavglpsipvhp
igyydaqkllekmggsappdsswrgslkvpynvgpgfvkmhihstnevtriynvigtlrg
avepdryvilgghrdswvfggidpqsgaavvheivrsfgtlkkegwrprrtilfaswdae
efgllgstewaeensrllqergvayinadssiegnytlrvdctplmyslvhnltkelksp
degfegkslyeswtkkspspefsgmprisklgsgndfevffqrlgiasgrarytkngypl
yhsvyetyelvekfydpmfkyhltvaqvrggmvfelansivlpfdcrdyavvlrkyadki
ysismkhpqemktysvsfdslfsavknfteiaskfserlqdfdnpivlrmmndqlmfler
afidplglpdrpfyrhviyapsshnkyagesfpgiydalfdieskvdpskawgevkrqiy
vaaftvqaaaetlseva