PDB entry 2c6h

View 2c6h on RCSB PDB site
Description: crystal structure of yc-17-bound cytochrome p450 pikc (cyp107l1)
Class: oxidoreductase
Keywords: oxidoreductase, cytochrome p450, pikc, cyp107l1, macrolide monooxygenase, antibiotic biosynthesis, heme, iron, metal-binding, monooxygenase, oxidoreductase antibiotic biosynthesis
Deposited on 2005-11-09, released 2006-07-03
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.195
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cytochrome p450 monooxygenase
    Species: STREPTOMYCES VENEZUELAE [TaxId:54571]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2c6ha_
  • Chain 'B':
    Compound: cytochrome p450 monooxygenase
    Species: STREPTOMYCES VENEZUELAE [TaxId:54571]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2c6hb_
  • Heterogens: HEM, PXI, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2c6hA (A:)
    mgsshhhhhhssglvprgshmrrtqqgttasppvldlgalgqdfaadpyptyarlraegp
    ahrvrtpegdevwlvvgydraravladprfskdwrnsttplteaeaalnhnmlesdpprh
    trlrklvareftmrrvellrprvqeivdglvdamlaapdgradlmeslawplpitvisel
    lgvpepdraafrvwtdafvfpddpaqaqtamaemsgylsrlidskrgqdgedllsalvrt
    sdedgsrltseellgmahillvaghettvnliangmyallshpdqlaalradmtlldgav
    eemlryegpvesatyrfpvepvdldgtvipagdtvlvvladahrtperfpdphrfdirrd
    taghlafghgihfcigaplarleariavrallercpdlaldvspgelvwypnpmirglka
    lpirwrrgreagrrtg
    

    Sequence, based on observed residues (ATOM records): (download)
    >2c6hA (A:)
    vldlgalgqdfaadpyptyarlraegpahrvrtpegdevwlvvgydraravladprfskd
    wrnsttplteaeaalnhnmlesdpprhtrlrklvareftmrrvellrprvqeivdglvda
    mlaapdgradlmeslawplpitvisellgvpepdraafrvwtdafvfpddpaqaqtamae
    msgylsrlidskrgqdgedllsalvrtsdedgsrltseellgmahillvaghettvnlia
    ngmyallshpdqlaalradmtlldgaveemlryegpvesatyrfpvepvdldgtvipagd
    tvlvvladahrtperfpdphrfdirrdtaghlafghgihfcigaplarleariavralle
    rcpdlaldvspgelvwypnpmirglkalpirwrr
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2c6hB (B:)
    mgsshhhhhhssglvprgshmrrtqqgttasppvldlgalgqdfaadpyptyarlraegp
    ahrvrtpegdevwlvvgydraravladprfskdwrnsttplteaeaalnhnmlesdpprh
    trlrklvareftmrrvellrprvqeivdglvdamlaapdgradlmeslawplpitvisel
    lgvpepdraafrvwtdafvfpddpaqaqtamaemsgylsrlidskrgqdgedllsalvrt
    sdedgsrltseellgmahillvaghettvnliangmyallshpdqlaalradmtlldgav
    eemlryegpvesatyrfpvepvdldgtvipagdtvlvvladahrtperfpdphrfdirrd
    taghlafghgihfcigaplarleariavrallercpdlaldvspgelvwypnpmirglka
    lpirwrrgreagrrtg
    

    Sequence, based on observed residues (ATOM records): (download)
    >2c6hB (B:)
    vldlgalgqdfaadpyptyarlraegpahrvrtpegdevwlvvgydraravladprfskd
    wrnsttplteaeaalnhnmlesdpprhtrlrklvareftmrrvellrprvqeivdglvda
    mlaapdgradlmeslawplpitvisellgvpepdraafrvwtdafvfpddpaqaqtamae
    msgylsrlidskrgqdgedllsalvrtsdedgsrltseellgmahillvaghettvnlia
    ngmyallshpdqlaalradmtlldgaveemlryegpvesatyrfpvepvdldgtvipagd
    tvlvvladahrtperfpdphrfdirrdtaghlafghgihfcigaplarleariavralle
    rcpdlaldvspgelvwypnpmirglkalpirwrrg