PDB entry 2c69

View 2c69 on RCSB PDB site
Description: Crystal structure of the human CDK2 complexed with the triazolopyrimidine inhibitor
Class: transferase
Keywords: transferase, serine/threonine protein kinase, cdk2, ATP-binding, cell cycle, mitosis, phosphorylation, triazolopyrimidine inhibitor, cell division, kinase, polymorphism, nucleotide-binding
Deposited on 2005-11-08, released 2005-12-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-04-24, with a file datestamp of 2019-04-19.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c69a_
  • Heterogens: CT8, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2c69A (A:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

    Sequence, based on observed residues (ATOM records): (download) 
    >2c69A (A:)
menfqkvekigegtygvvykarnkltgevvalkkirlvpstaireisllkelnhpnivkl
ldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhr
dlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyystavdi
wslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarq
dfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl