PDB entry 2c5y
View 2c5y on RCSB PDB site
Description: differential binding of inhibitors to active and inactive cdk2 provides insights for drug design
Class: transferase
Keywords: cdk2, drug design, ATP-binding, cell cycle, cell division, kinase, mitosis, nucleotide-binding, phosphorylation, serine/threonine-protein kinase, transferase
Deposited on
2005-11-03, released
2006-03-01
The last revision prior to the SCOPe 2.03 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.172
AEROSPACI score: 0.34
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Cell division protein kinase 2
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d2c5ya_ - Heterogens: MTW, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2c5yA (A:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
Sequence, based on observed residues (ATOM records): (download)
>2c5yA (A:)
menfqkvekigegtygvvykarnkltgevvalkkigvpstaireisllkelnhpnivkll
dvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrd
lkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyystavdiw
slgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqd
fskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlr