PDB entry 2c59

View 2c59 on RCSB PDB site
Description: gdp-mannose-3', 5' -epimerase (arabidopsis thaliana), with gdp-alpha-d-mannose and gdp-beta-l-galactose bound in the active site.
Class: isomerase
Keywords: 3' 5'-epimerase, short chain dehydratase/reductase, GDP-mannose, GDP-gulose, GDP-galactose, keto intermediate, vitamin c, ascorbate biosynthesis, isomerase
Deposited on 2005-10-26, released 2005-11-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-08, with a file datestamp of 2019-05-03.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: GDP-mannose-3', 5'-epimerase
    Species: ARABIDOPSIS THALIANA [TaxId:3702]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c59a1
  • Chain 'B':
    Compound: GDP-mannose-3', 5'-epimerase
    Species: ARABIDOPSIS THALIANA [TaxId:3702]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c59b_
  • Heterogens: GDD, GDC, NAD, FMT, BTB, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2c59A (A:)
    gamgttngtdygaytykelereqywpsenlkisitgaggfiashiarrlkheghyviasd
    wkknehmtedmfcdefhlvdlrvmenclkvtegvdhvfnlaadmggmgfiqsnhsvimyn
    ntmisfnmieaaringikrffyassaciypefkqlettnvslkesdawpaepqdayglek
    lateelckhynkdfgiecrigrfhniygpfgtwkggrekapaafcrkaqtstdrfemwgd
    glqtrsftfidecvegvlrltksdfrepvnigsdemvsmnemaemvlsfeekklpihhip
    gpegvrgrnsdnnlikeklgwapnmrlkeglrityfwikeqiekekakgsdvslygsskv
    vgtqapvqlgslraadgke
    

    Sequence, based on observed residues (ATOM records): (download)
    >2c59A (A:)
    ytykelereqywpsenlkisitgaggfiashiarrlkheghyviasdwkknehmtedmfc
    defhlvdlrvmenclkvtegvdhvfnlaadmggmgfiqsnhsvimynntmisfnmieaar
    ingikrffyassaciypefkqlettnvslkesdawpaepqdaygleklateelckhynkd
    fgiecrigrfhniygpfgtwkggrekapaafcrkaqtstdrfemwgdglqtrsftfidec
    vegvlrltksdfrepvnigsdemvsmnemaemvlsfeekklpihhipgpegvrgrnsdnn
    likeklgwapnmrlkeglrityfwikeqiekekakgsdvslygsskvvgtqapvqlgslr
    aadg
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2c59B (B:)
    gamgttngtdygaytykelereqywpsenlkisitgaggfiashiarrlkheghyviasd
    wkknehmtedmfcdefhlvdlrvmenclkvtegvdhvfnlaadmggmgfiqsnhsvimyn
    ntmisfnmieaaringikrffyassaciypefkqlettnvslkesdawpaepqdayglek
    lateelckhynkdfgiecrigrfhniygpfgtwkggrekapaafcrkaqtstdrfemwgd
    glqtrsftfidecvegvlrltksdfrepvnigsdemvsmnemaemvlsfeekklpihhip
    gpegvrgrnsdnnlikeklgwapnmrlkeglrityfwikeqiekekakgsdvslygsskv
    vgtqapvqlgslraadgke
    

    Sequence, based on observed residues (ATOM records): (download)
    >2c59B (B:)
    gaytykelereqywpsenlkisitgaggfiashiarrlkheghyviasdwkknehmtedm
    fcdefhlvdlrvmenclkvtegvdhvfnlaadmggmgfiqsnhsvimynntmisfnmiea
    aringikrffyassaciypefkqlettnvslkesdawpaepqdaygleklateelckhyn
    kdfgiecrigrfhniygpfgtwkggrekapaafcrkaqtstdrfemwgdglqtrsftfid
    ecvegvlrltksdfrepvnigsdemvsmnemaemvlsfeekklpihhipgpegvrgrnsd
    nnlikeklgwapnmrlkeglrityfwikeqiekekakgsdvslygsskvvgtqapvqlgs
    lr