PDB entry 2c4k

View 2c4k on RCSB PDB site
Description: Crystal structure of human phosphoribosylpyrophosphate synthetase- associated protein 39 (PAP39)
Class: regulatory protein
Keywords: nucleotide biosynthesis, synthetase, ligase, regulatory protein
Deposited on 2005-10-20, released 2005-10-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-17, with a file datestamp of 2018-01-12.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: phosphoribosyl pyrophosphate synthetase-associated protein 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c4ka1, d2c4ka2
  • Chain 'B':
    Compound: phosphoribosyl pyrophosphate synthetase-associated protein 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c4kb1, d2c4kb2
  • Chain 'C':
    Compound: phosphoribosyl pyrophosphate synthetase-associated protein 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c4kc1, d2c4kc2
  • Chain 'D':
    Compound: phosphoribosyl pyrophosphate synthetase-associated protein 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c4kd1, d2c4kd2
  • Chain 'E':
    Compound: phosphoribosyl pyrophosphate synthetase-associated protein 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c4ke1, d2c4ke2
  • Chain 'F':
    Compound: phosphoribosyl pyrophosphate synthetase-associated protein 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c4kf1, d2c4kf2
  • Heterogens: SO4, TAM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2c4kA (A:)
mhhhhhhssgvdlgtenlyfqsmrtgyrvfsanstaactelakriterlgaelgksvvyq
etngetrveikesvrgqdifiiqtiprdvntavmellimayalktacarniigvipyfpy
skqskmrkrgsivckllasmlakaglthiitmdlhqkeiqgffsfpvdnlraspfllqyi
qeeipnyrnavivakspdaakraqsyaerlrlglavihgeaqcteldmddgrhsppmvkn
atvhpglelplmmakekppitvvgdvggriaiivddiiddvesfvaaaeilkergaykiy
vmathgilsaeaprlieessvdevvvtntvphevqklqcpkiktvdislilseairrihn
gesmaylfrn

    Sequence, based on observed residues (ATOM records): (download) 
    >2c4kA (A:)
gyrvfsanstaactelakriterlgaelgksvvyqetngetrveikesvrgqdifiiqti
prdvntavmellimayalktacarniigvipyfpyskqskmrkrgsivckllasmlakag
lthiitmdlhqkeiqgffsfpvdnlraspfllqyiqeeipnyrnavivakspdaakraqs
yaerlrlglavihppitvvgdvggriaiivddiiddvesfvaaaeilkergaykiyvmat
hgilsaeaprlieessvdevvvtntvphevqklqcpkiktvdislilseairrihngesm
aylfr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2c4kB (B:)
mhhhhhhssgvdlgtenlyfqsmrtgyrvfsanstaactelakriterlgaelgksvvyq
etngetrveikesvrgqdifiiqtiprdvntavmellimayalktacarniigvipyfpy
skqskmrkrgsivckllasmlakaglthiitmdlhqkeiqgffsfpvdnlraspfllqyi
qeeipnyrnavivakspdaakraqsyaerlrlglavihgeaqcteldmddgrhsppmvkn
atvhpglelplmmakekppitvvgdvggriaiivddiiddvesfvaaaeilkergaykiy
vmathgilsaeaprlieessvdevvvtntvphevqklqcpkiktvdislilseairrihn
gesmaylfrn

    Sequence, based on observed residues (ATOM records): (download) 
    >2c4kB (B:)
gyrvfsanstaactelakriterlgaelgksvvyqetngetrveikesvrgqdifiiqti
prdvntavmellimayalktacarniigvipyfpyskqskmrkrgsivckllasmlakag
lthiitmdlhqkeiqgffsfpvdnlraspfllqyiqeeipnyrnavivakspdaakraqs
yaerlrlglavihppitvvgdvggriaiivddiiddvesfvaaaeilkergaykiyvmat
hgilsaeaprlieessvdevvvtntvphevqklqcpkiktvdislilseairrihngesm
aylfr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2c4kC (C:)
mhhhhhhssgvdlgtenlyfqsmrtgyrvfsanstaactelakriterlgaelgksvvyq
etngetrveikesvrgqdifiiqtiprdvntavmellimayalktacarniigvipyfpy
skqskmrkrgsivckllasmlakaglthiitmdlhqkeiqgffsfpvdnlraspfllqyi
qeeipnyrnavivakspdaakraqsyaerlrlglavihgeaqcteldmddgrhsppmvkn
atvhpglelplmmakekppitvvgdvggriaiivddiiddvesfvaaaeilkergaykiy
vmathgilsaeaprlieessvdevvvtntvphevqklqcpkiktvdislilseairrihn
gesmaylfrn

    Sequence, based on observed residues (ATOM records): (download) 
    >2c4kC (C:)
gyrvfsanstaactelakriterlgaelgksvvyqetngetrveikesvrgqdifiiqti
prdvntavmellimayalktacarniigvipyfpyskqskmrkrgsivckllasmlakag
lthiitmdlhqkeiqgffsfpvdnlraspfllqyiqeeipnyrnavivakspdaakraqs
yaerlrlglavihppitvvgdvggriaiivddiiddvesfvaaaeilkergaykiyvmat
hgilsaeaprlieessvdevvvtntvphevqklqcpkiktvdislilseairrihngesm
aylfr

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2c4kD (D:)
mhhhhhhssgvdlgtenlyfqsmrtgyrvfsanstaactelakriterlgaelgksvvyq
etngetrveikesvrgqdifiiqtiprdvntavmellimayalktacarniigvipyfpy
skqskmrkrgsivckllasmlakaglthiitmdlhqkeiqgffsfpvdnlraspfllqyi
qeeipnyrnavivakspdaakraqsyaerlrlglavihgeaqcteldmddgrhsppmvkn
atvhpglelplmmakekppitvvgdvggriaiivddiiddvesfvaaaeilkergaykiy
vmathgilsaeaprlieessvdevvvtntvphevqklqcpkiktvdislilseairrihn
gesmaylfrn

    Sequence, based on observed residues (ATOM records): (download) 
    >2c4kD (D:)
gyrvfsanstaactelakriterlgaelgksvvyqetngetrveikesvrgqdifiiqti
prdvntavmellimayalktacarniigvipyfpyskqskmrkrgsivckllasmlakag
lthiitmdlhqkeiqgffsfpvdnlraspfllqyiqeeipnyrnavivakspdaakraqs
yaerlrlglavihppitvvgdvggriaiivddiiddvesfvaaaeilkergaykiyvmat
hgilsaeaprlieessvdevvvtntvphevqklqcpkiktvdislilseairrihngesm
aylfr

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2c4kE (E:)
mhhhhhhssgvdlgtenlyfqsmrtgyrvfsanstaactelakriterlgaelgksvvyq
etngetrveikesvrgqdifiiqtiprdvntavmellimayalktacarniigvipyfpy
skqskmrkrgsivckllasmlakaglthiitmdlhqkeiqgffsfpvdnlraspfllqyi
qeeipnyrnavivakspdaakraqsyaerlrlglavihgeaqcteldmddgrhsppmvkn
atvhpglelplmmakekppitvvgdvggriaiivddiiddvesfvaaaeilkergaykiy
vmathgilsaeaprlieessvdevvvtntvphevqklqcpkiktvdislilseairrihn
gesmaylfrn

    Sequence, based on observed residues (ATOM records): (download) 
    >2c4kE (E:)
gyrvfsanstaactelakriterlgaelgksvvyqetngetrveikesvrgqdifiiqti
prdvntavmellimayalktacarniigvipyfpyskqskmrkrgsivckllasmlakag
lthiitmdlhqkeiqgffsfpvdnlraspfllqyiqeeipnyrnavivakspdaakraqs
yaerlrlglavihppitvvgdvggriaiivddiiddvesfvaaaeilkergaykiyvmat
hgilsaeaprlieessvdevvvtntvphevqklqcpkiktvdislilseairrihngesm
aylfr

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2c4kF (F:)
mhhhhhhssgvdlgtenlyfqsmrtgyrvfsanstaactelakriterlgaelgksvvyq
etngetrveikesvrgqdifiiqtiprdvntavmellimayalktacarniigvipyfpy
skqskmrkrgsivckllasmlakaglthiitmdlhqkeiqgffsfpvdnlraspfllqyi
qeeipnyrnavivakspdaakraqsyaerlrlglavihgeaqcteldmddgrhsppmvkn
atvhpglelplmmakekppitvvgdvggriaiivddiiddvesfvaaaeilkergaykiy
vmathgilsaeaprlieessvdevvvtntvphevqklqcpkiktvdislilseairrihn
gesmaylfrn

    Sequence, based on observed residues (ATOM records): (download) 
    >2c4kF (F:)
gyrvfsanstaactelakriterlgaelgksvvyqetngetrveikesvrgqdifiiqti
prdvntavmellimayalktacarniigvipyfpyskqskmrkrgsivckllasmlakag
lthiitmdlhqkeiqgffsfpvdnlraspfllqyiqeeipnyrnavivakspdaakraqs
yaerlrlglavihppitvvgdvggriaiivddiiddvesfvaaaeilkergaykiyvmat
hgilsaeaprlieessvdevvvtntvphevqklqcpkiktvdislilseairrihngesm
aylfr