PDB entry 2c4f

View 2c4f on RCSB PDB site
Description: crystal structure of factor vii.stf complexed with pd0297121
Class: hydrolase
Keywords: blood coagulation, serine protease, egf, egf-like domain, gla, receptor enzyme, glycoprotein, hydrolase, protease, hydroxylation, lipoprotein, palmitate, transmembrane
Deposited on 2005-10-18, released 2006-10-18
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.72 Å
R-factor: 0.2285
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: coagulation factor vii precursor
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2c4fh1
  • Chain 'L':
    Compound: coagulation factor vii precursor
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Domains in SCOPe 2.03: d2c4fl1, d2c4fl2, d2c4fl3
  • Chain 'T':
    Compound: tissue factor precursor
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'U':
    Compound: tissue factor precursor
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Domains in SCOPe 2.03: d2c4fu1
  • Heterogens: CA, GIL, GLC, FUC, NAG, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2c4fH (H:)
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >2c4fL (L:)
anafleelrpgslereckeeqcsfeeareifkdaertklfwisysdgdqcasspcqnggs
ckdqlqsyicfclpafegrncethkddqlicvnenggceqycsdhtgtkrscrchegysl
ladgvsctptveypcgkipile

    Sequence, based on observed residues (ATOM records): (download) 
    >2c4fL (L:)
fleelrpgslereckeeqcsfeeareifkdaertklfwisysdgdqcasspcqnggsckd
qlqsyicfclpafegrncethkddqlicvnenggceqycsdhtgtkrscrchegysllad
gvsctptveypcgkipile

  • Chain 'T':
    No sequence available.

  • Chain 'U':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2c4fU (U:)
eplyenspeftpyletnlgqptiqsfeqvgtkvnvtvedertlvrrnntflslrdvfgkd
liytlyywsgkktaktntneflidvdkgenycfsvqavipsrtvnrkstdspvecm