PDB entry 2c2l

View 2c2l on RCSB PDB site
Description: Crystal structure of the CHIP U-box E3 ubiquitin ligase
Class: chaperone
Keywords: chaperone, e3 ligase, ubiquitinylation, tpr, heat-shock protein complex
Deposited on 2005-09-29, released 2005-11-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-15, with a file datestamp of 2019-05-10.
Experiment type: XRAY
Resolution: 3.3 Å
R-factor: N/A
AEROSPACI score: 0.09 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: carboxy terminus of hsp70-interacting protein
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c2la1, d2c2la2
  • Chain 'B':
    Compound: carboxy terminus of hsp70-interacting protein
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c2lb1, d2c2lb2
  • Chain 'C':
    Compound: carboxy terminus of hsp70-interacting protein
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c2lc1, d2c2lc2
  • Chain 'D':
    Compound: carboxy terminus of hsp70-interacting protein
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c2ld1, d2c2ld2
  • Chain 'E':
    Compound: hsp90
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: hsp90
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: hsp90
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: hsp90
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: SO4, NI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2c2lA (A:)
spsaqelkeqgnrlfvgrkypeaaacygraitrnplvavyytnralcylkmqqpeqalad
crraleldgqsvkahfflgqcqlemesydeaianlqrayslakeqrlnfgddipsalria
kkkrwnsieerrihqeselhsyltrliaaerereleecqrnhegheddghiraqqaciea
khdkymadmdelfsqvdekrkkrdipdylcgkisfelmrepcitpsgitydrkdieehlq
rvghfnpvtrspltqeqlipnlamkevidafisengwvedy

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2c2lB (B:)
spsaqelkeqgnrlfvgrkypeaaacygraitrnplvavyytnralcylkmqqpeqalad
crraleldgqsvkahfflgqcqlemesydeaianlqrayslakeqrlnfgddipsalria
kkkrwnsieerrihqeselhsyltrliaaerereleecqrnhegheddghiraqqaciea
khdkymadmdelfsqvdekrkkrdipdylcgkisfelmrepcitpsgitydrkdieehlq
rvghfnpvtrspltqeqlipnlamkevidafisengwvedy

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2c2lC (C:)
spsaqelkeqgnrlfvgrkypeaaacygraitrnplvavyytnralcylkmqqpeqalad
crraleldgqsvkahfflgqcqlemesydeaianlqrayslakeqrlnfgddipsalria
kkkrwnsieerrihqeselhsyltrliaaerereleecqrnhegheddghiraqqaciea
khdkymadmdelfsqvdekrkkrdipdylcgkisfelmrepcitpsgitydrkdieehlq
rvghfnpvtrspltqeqlipnlamkevidafisengwvedy

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2c2lD (D:)
spsaqelkeqgnrlfvgrkypeaaacygraitrnplvavyytnralcylkmqqpeqalad
crraleldgqsvkahfflgqcqlemesydeaianlqrayslakeqrlnfgddipsalria
kkkrwnsieerrihqeselhsyltrliaaerereleecqrnhegheddghiraqqaciea
khdkymadmdelfsqvdekrkkrdipdylcgkisfelmrepcitpsgitydrkdieehlq
rvghfnpvtrspltqeqlipnlamkevidafisengwvedy

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.