PDB entry 2c28

View 2c28 on RCSB PDB site
Description: efficient and high fidelity incorporation of dctp opposite 7,8-dihydro-8-oxodeoxyguanosine by sulfolobus solfataricus DNA polymerase dpo4
Class: polymerase
Keywords: 7,8-dihydro-8-oxodeoxyguanosine, p2 DNA polymerase IV, translesion DNA polymerase, ddgtp, nucleotidyltransferase, transferase, DNA damage, DNA repair, DNA replication, DNA-binding, DNA-directed DNA polymerase, magnesium, metal-binding, mutator protein
Deposited on 2005-09-26, released 2005-11-29
The last revision prior to the SCOP 1.73 freeze date was dated 2005-11-29, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.27 Å
R-factor: 0.239
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase IV
    Species: SULFOLOBUS SOLFATARICUS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2c28a1, d2c28a2
  • Chain 'P':
    Compound: 5'-d(*gp*gp*gp*gp*gp*ap*ap*gp*gp*ap *tp*tp*c)-3'
  • Chain 'T':
    Compound: 5'-d(tp*cp*ap*c 8ogp*gp*ap*ap*tp*cp*cp*tp *tp*cp*cp*cp*cp*c)-3'
  • Heterogens: CA, DG3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2c28A (A:)
hhhhhhmivlfvdfdyfyaqveevlnpslkgkpvvvcvfsgrfedsgavatanyearkfg
vkagipiveakkilpnavylpmrkevyqqvssrimnllreysekieiasideayldisdk
vrdyreaynlgleiknkilekekitvtvgisknkvfakiaadmakpngikviddeevkrl
ireldiadvpgignitaeklkklginklvdtlsiefdklkgmigeakakylislardeyn
epirtrvrksigrivtmkrnsrnleeikpylfraieesyykldkripkaihvvavtedld
ivsrgrtfphgisketaysesvkllqkileederkirrigvrfskfieaigldkffdt

    Sequence, based on observed residues (ATOM records): (download) 
    >2c28A (A:)
mivlfvdfdyfyaqveevlnpslkgkpvvvcvfsgrfedsgavatanyearkfgvkagip
iveakkilpnavylpmrkevyqqvssrimnllreysekieiasideayldisdkvrdyre
aynlgleiknkilekekitvtvgisknkvfakiaadmakpngikviddeevkrlireldi
advpgignitaeklkklginklvdtlsiefdklkgmigeakakylislardeynepirtr
vrksigrivtmkrnsrnleeikpylfraieesyykldkripkaihvvavtedldivsrgr
tfphgisketaysesvkllqkileederkirrigvrfskfie

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.