PDB entry 2c13

View 2c13 on RCSB PDB site
Description: 5-hydroxy-levulinic acid bound to porphobilinogen synthase from pseudomonas aeruginosa
Class: lyase
Keywords: enzyme mechanism, metalloenzyme, porphobilinogen synthase, cocrystallization, lyase, porphyrin biosynthesis
Deposited on 2005-09-11, released 2006-06-20
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: 0.155
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: delta-aminolevulinic acid dehydratase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q59643
      • engineered mutation (198)
    Domains in SCOPe 2.06: d2c13a_
  • Chain 'B':
    Compound: delta-aminolevulinic acid dehydratase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q59643
      • engineered mutation (198)
    Domains in SCOPe 2.06: d2c13b_
  • Heterogens: MG, CL, PEG, K, PGE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2c13A (A:)
msftpanraypytrlrrnrrddfsrrlvrenvltvddlilpvfvldgvnqresipsmpgv
erlsidqllieaeewvalgipalalfpvtpvekksldaaeaynpegiaqratralrerfp
elgiitdvaldpftthgqdgildddgyvlndvsidvlvrqalshaeagaqvvapsdmmdg
rigairealesaghtnvrvmaysaxyasayygpfrdavgsasnlgkgnkatyqmdpansd
ealhevaadlaegadmvmvxpgmpyldivrrvkdefraptfvyqvsgeyamhmgaiqngw
laesvilesltafkragadgiltyfakqaaeqlrrgr

    Sequence, based on observed residues (ATOM records): (download) 
    >2c13A (A:)
ftpanraypytrlrrnrrddfsrrlvrenvltvddlilpvfvldgvnqresipsmpgver
lsidqllieaeewvalgipalalfpvtpvekksldaaeaynpegiaqratralrerfpel
giitdvaldpftthgqdgildddgyvlndvsidvlvrqalshaeagaqvvapsdmmdgri
gairealesaghtnvrvmaysaxyasayygpfrdavgsasnlgkgnkatyqmdpansdea
lhevaadlaegadmvmvxpgmpyldivrrvkdefraptfvyqvsgeyamhmgaiqngwla
esvilesltafkragadgiltyfakqaaeqlrrg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2c13B (B:)
msftpanraypytrlrrnrrddfsrrlvrenvltvddlilpvfvldgvnqresipsmpgv
erlsidqllieaeewvalgipalalfpvtpvekksldaaeaynpegiaqratralrerfp
elgiitdvaldpftthgqdgildddgyvlndvsidvlvrqalshaeagaqvvapsdmmdg
rigairealesaghtnvrvmaysaxyasayygpfrdavgsasnlgkgnkatyqmdpansd
ealhevaadlaegadmvmvxpgmpyldivrrvkdefraptfvyqvsgeyamhmgaiqngw
laesvilesltafkragadgiltyfakqaaeqlrrgr

    Sequence, based on observed residues (ATOM records): (download) 
    >2c13B (B:)
sftpanraypytrlrrnrrddfsrrlvrenvltvddlilpvfvldgvnqresipsmpgve
rlsidqllieaeewvalgipalalfpvtpvekksldaaeaynpegiaqratralrerfpe
lgiitdvaldpftthgqdgildddgyvlndvsidvlvrqalshaeagaqvvapsdmmdgr
igairealesaghtnvrvmaysaxyasayygpfrdavgsasgnkatyqmdpansdealhe
vaadlaegadmvmvxpgmpyldivrrvkdefraptfvyqvsgeyamhmgaiqngwlaesv
ilesltafkragadgiltyfakqaaeqlrrg