PDB entry 2c12

View 2c12 on RCSB PDB site
Description: Crystal Structure of Nitroalkane Oxidase in Complex with Spermine, a Competitive Inhibitor
Class: oxidoreductase
Keywords: oxidoreductase, flavoenzyme, nitroalkane, acyl-coa dehydrogenase, long cell edge, fad, inhibitor, flavoprotein
Deposited on 2005-09-10, released 2006-02-01
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-12-04, with a file datestamp of 2013-11-29.
Experiment type: XRAY
Resolution: 2.07 Å
R-factor: 0.19
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: nitroalkane oxidase
    Species: FUSARIUM OXYSPORUM [TaxId:5507]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2c12a1, d2c12a2
  • Chain 'B':
    Compound: nitroalkane oxidase
    Species: FUSARIUM OXYSPORUM [TaxId:5507]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2c12b1, d2c12b2
  • Chain 'C':
    Compound: nitroalkane oxidase
    Species: FUSARIUM OXYSPORUM [TaxId:5507]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2c12c1, d2c12c2
  • Chain 'D':
    Compound: nitroalkane oxidase
    Species: FUSARIUM OXYSPORUM [TaxId:5507]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2c12d1, d2c12d2
  • Chain 'E':
    Compound: nitroalkane oxidase
    Species: FUSARIUM OXYSPORUM [TaxId:5507]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2c12e1, d2c12e2
  • Chain 'F':
    Compound: nitroalkane oxidase
    Species: FUSARIUM OXYSPORUM [TaxId:5507]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2c12f1, d2c12f2
  • Heterogens: FAD, GOL, SPM, PE4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2c12A (A:)
mvdfklspsqlearrhaqafantvltkasaeystqkdqlsrfqatrpfyreavrhglika
qvpiplggtmeslvhesiileelfavepatsitivatalglmpvilcdspslqekflkpf
isgegeplaslmhsepngtanwlqkggpglqttarkvgnewvisgeklwpsnsggwdykg
adlacvvcrvsddpskpqdpnvdpatqiavllvtretiannkkdayqilgepelaghitt
sgphtrftefhvphenllctpglkaqglvetafamsaalvgamaigtaraafeealvfak
sdtrggskhiiehqsvadklidckirletsrllvwkavttledealewkvklemamqtki
yttdvavecvidamkavgmksyakdmsfprllnevmcyplfdggniglrrrqmqrvmale
dyepwaatygsskvdksrl

    Sequence, based on observed residues (ATOM records): (download) 
    >2c12A (A:)
vdfklspsqlearrhaqafantvltkasaeystqkdqlsrfqatrpfyreavrhglikaq
vpiplggtmeslvhesiileelfavepatsitivatalglmpvilcdspslqekflkpfi
sgegeplaslmhsepngtanwlqkggpglqttarkvgnewvisgeklwpsnsggwdykga
dlacvvcrvsddpskpqdpnvdpatqiavllvtretiannkkdayqilgepelaghitts
gphtrftefhvphenllctpglkaqglvetafamsaalvgamaigtaraafeealvfaks
dtrggskhiiehqsvadklidckirletsrllvwkavttledealewkvklemamqtkiy
ttdvavecvidamkavgmksyakdmsfprllnevmcyplfdggniglrrrqmqrvmaled
yepwaatygs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2c12B (B:)
mvdfklspsqlearrhaqafantvltkasaeystqkdqlsrfqatrpfyreavrhglika
qvpiplggtmeslvhesiileelfavepatsitivatalglmpvilcdspslqekflkpf
isgegeplaslmhsepngtanwlqkggpglqttarkvgnewvisgeklwpsnsggwdykg
adlacvvcrvsddpskpqdpnvdpatqiavllvtretiannkkdayqilgepelaghitt
sgphtrftefhvphenllctpglkaqglvetafamsaalvgamaigtaraafeealvfak
sdtrggskhiiehqsvadklidckirletsrllvwkavttledealewkvklemamqtki
yttdvavecvidamkavgmksyakdmsfprllnevmcyplfdggniglrrrqmqrvmale
dyepwaatygsskvdksrl

    Sequence, based on observed residues (ATOM records): (download) 
    >2c12B (B:)
vdfklspsqlearrhaqafantvltkasaeystqkdqlsrfqatrpfyreavrhglikaq
vpiplggtmeslvhesiileelfavepatsitivatalglmpvilcdspslqekflkpfi
sgegeplaslmhsepngtanwlqkggpglqttarkvgnewvisgeklwpsnsggwdykga
dlacvvcrvsddpskpqdpnvdpatqiavllvtretiannkkdayqilgepelaghitts
gphtrftefhvphenllctpglkaqglvetafamsaalvgamaigtaraafeealvfaks
dtrggskhiiehqsvadklidckirletsrllvwkavttledealewkvklemamqtkiy
ttdvavecvidamkavgmksyakdmsfprllnevmcyplfdggniglrrrqmqrvmaled
yepwaatygs

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2c12C (C:)
mvdfklspsqlearrhaqafantvltkasaeystqkdqlsrfqatrpfyreavrhglika
qvpiplggtmeslvhesiileelfavepatsitivatalglmpvilcdspslqekflkpf
isgegeplaslmhsepngtanwlqkggpglqttarkvgnewvisgeklwpsnsggwdykg
adlacvvcrvsddpskpqdpnvdpatqiavllvtretiannkkdayqilgepelaghitt
sgphtrftefhvphenllctpglkaqglvetafamsaalvgamaigtaraafeealvfak
sdtrggskhiiehqsvadklidckirletsrllvwkavttledealewkvklemamqtki
yttdvavecvidamkavgmksyakdmsfprllnevmcyplfdggniglrrrqmqrvmale
dyepwaatygsskvdksrl

    Sequence, based on observed residues (ATOM records): (download) 
    >2c12C (C:)
vdfklspsqlearrhaqafantvltkasaeystqkdqlsrfqatrpfyreavrhglikaq
vpiplggtmeslvhesiileelfavepatsitivatalglmpvilcdspslqekflkpfi
sgegeplaslmhsepngtanwlqkggpglqttarkvgnewvisgeklwpsnsggwdykga
dlacvvcrvsddpskpqdpnvdpatqiavllvtretiannkkdayqilgepelaghitts
gphtrftefhvphenllctpglkaqglvetafamsaalvgamaigtaraafeealvfaks
dtrggskhiiehqsvadklidckirletsrllvwkavttledealewkvklemamqtkiy
ttdvavecvidamkavgmksyakdmsfprllnevmcyplfdggniglrrrqmqrvmaled
yepwaatygs

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2c12D (D:)
mvdfklspsqlearrhaqafantvltkasaeystqkdqlsrfqatrpfyreavrhglika
qvpiplggtmeslvhesiileelfavepatsitivatalglmpvilcdspslqekflkpf
isgegeplaslmhsepngtanwlqkggpglqttarkvgnewvisgeklwpsnsggwdykg
adlacvvcrvsddpskpqdpnvdpatqiavllvtretiannkkdayqilgepelaghitt
sgphtrftefhvphenllctpglkaqglvetafamsaalvgamaigtaraafeealvfak
sdtrggskhiiehqsvadklidckirletsrllvwkavttledealewkvklemamqtki
yttdvavecvidamkavgmksyakdmsfprllnevmcyplfdggniglrrrqmqrvmale
dyepwaatygsskvdksrl

    Sequence, based on observed residues (ATOM records): (download) 
    >2c12D (D:)
vdfklspsqlearrhaqafantvltkasaeystqkdqlsrfqatrpfyreavrhglikaq
vpiplggtmeslvhesiileelfavepatsitivatalglmpvilcdspslqekflkpfi
sgegeplaslmhsepngtanwlqkggpglqttarkvgnewvisgeklwpsnsggwdykga
dlacvvcrvsddpskpqdpnvdpatqiavllvtretiannkkdayqilgepelaghitts
gphtrftefhvphenllctpglkaqglvetafamsaalvgamaigtaraafeealvfaks
dtrggskhiiehqsvadklidckirletsrllvwkavttledealewkvklemamqtkiy
ttdvavecvidamkavgmksyakdmsfprllnevmcyplfdggniglrrrqmqrvmaled
yepwaatygs

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2c12E (E:)
mvdfklspsqlearrhaqafantvltkasaeystqkdqlsrfqatrpfyreavrhglika
qvpiplggtmeslvhesiileelfavepatsitivatalglmpvilcdspslqekflkpf
isgegeplaslmhsepngtanwlqkggpglqttarkvgnewvisgeklwpsnsggwdykg
adlacvvcrvsddpskpqdpnvdpatqiavllvtretiannkkdayqilgepelaghitt
sgphtrftefhvphenllctpglkaqglvetafamsaalvgamaigtaraafeealvfak
sdtrggskhiiehqsvadklidckirletsrllvwkavttledealewkvklemamqtki
yttdvavecvidamkavgmksyakdmsfprllnevmcyplfdggniglrrrqmqrvmale
dyepwaatygsskvdksrl

    Sequence, based on observed residues (ATOM records): (download) 
    >2c12E (E:)
vdfklspsqlearrhaqafantvltkasaeystqkdqlsrfqatrpfyreavrhglikaq
vpiplggtmeslvhesiileelfavepatsitivatalglmpvilcdspslqekflkpfi
sgegeplaslmhsepngtanwlqkggpglqttarkvgnewvisgeklwpsnsggwdykga
dlacvvcrvsddpskpqdpnvdpatqiavllvtretiannkkdayqilgepelaghitts
gphtrftefhvphenllctpglkaqglvetafamsaalvgamaigtaraafeealvfaks
dtrggskhiiehqsvadklidckirletsrllvwkavttledealewkvklemamqtkiy
ttdvavecvidamkavgmksyakdmsfprllnevmcyplfdggniglrrrqmqrvmaled
yepwaatygs

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2c12F (F:)
mvdfklspsqlearrhaqafantvltkasaeystqkdqlsrfqatrpfyreavrhglika
qvpiplggtmeslvhesiileelfavepatsitivatalglmpvilcdspslqekflkpf
isgegeplaslmhsepngtanwlqkggpglqttarkvgnewvisgeklwpsnsggwdykg
adlacvvcrvsddpskpqdpnvdpatqiavllvtretiannkkdayqilgepelaghitt
sgphtrftefhvphenllctpglkaqglvetafamsaalvgamaigtaraafeealvfak
sdtrggskhiiehqsvadklidckirletsrllvwkavttledealewkvklemamqtki
yttdvavecvidamkavgmksyakdmsfprllnevmcyplfdggniglrrrqmqrvmale
dyepwaatygsskvdksrl

    Sequence, based on observed residues (ATOM records): (download) 
    >2c12F (F:)
vdfklspsqlearrhaqafantvltkasaeystqkdqlsrfqatrpfyreavrhglikaq
vpiplggtmeslvhesiileelfavepatsitivatalglmpvilcdspslqekflkpfi
sgegeplaslmhsepngtanwlqkggpglqttarkvgnewvisgeklwpsnsggwdykga
dlacvvcrvsddpskpqdpnvdpatqiavllvtretiannkkdayqilgepelaghitts
gphtrftefhvphenllctpglkaqglvetafamsaalvgamaigtaraafeealvfaks
dtrggskhiiehqsvadklidckirletsrllvwkavttledealewkvklemamqtkiy
ttdvavecvidamkavgmksyakdmsfprllnevmcyplfdggniglrrrqmqrvmaled
yepwaatygs