PDB entry 2c0a

View 2c0a on RCSB PDB site
Description: Mechanism of the Class I KDPG aldolase
Class: lyase
Keywords: aldolase, lyase, multifunctional enzyme, schiff base
Deposited on 2005-08-29, released 2005-09-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-08-30, with a file datestamp of 2017-08-25.
Experiment type: XRAY
Resolution: 1.55 Å
R-factor: N/A
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: khg/kdpg aldolase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • PDB 2C0A
      • engineered mutation (45)
    • Uniprot P10177 (1-213)
    Domains in SCOPe 2.08: d2c0aa_
  • Chain 'B':
    Compound: khg/kdpg aldolase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • PDB 2C0A (0-0)
      • engineered mutation (45)
    • Uniprot P10177 (1-213)
    Domains in SCOPe 2.08: d2c0ab_
  • Chain 'C':
    Compound: khg/kdpg aldolase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • PDB 2C0A
      • engineered mutation (45)
    • Uniprot P10177 (1-213)
    Domains in SCOPe 2.08: d2c0ac_
  • Heterogens: PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2c0aA (A:)
amknwktsaesilttgpvvpvivvkklehavpmakalvaggvrvlnvtlrtecavdaira
iakevpeaivgagtvlnpqqlaevteagaqfaispgltepllkaategtiplipgistvs
elmlgmdyglkefkffpaeanggvkalqaiagpfsqvrfcptggispanyrdylalksvl
ciggswlvpadaleagdydritklareavegakl

    Sequence, based on observed residues (ATOM records): (download) 
    >2c0aA (A:)
mknwktsaesilttgpvvpvivvkklehavpmakalvaggvrvlnvtlrtecavdairai
akevpeaivgagtvlnpqqlaevteagaqfaispgltepllkaategtiplipgistvse
lmlgmdyglkefkffpaeanggvkalqaiagpfsqvrfcptggispanyrdylalksvlc
iggswlvpadaleagdydritklareavegakl

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2c0aB (B:)
amknwktsaesilttgpvvpvivvkklehavpmakalvaggvrvlnvtlrtecavdaira
iakevpeaivgagtvlnpqqlaevteagaqfaispgltepllkaategtiplipgistvs
elmlgmdyglkefkffpaeanggvkalqaiagpfsqvrfcptggispanyrdylalksvl
ciggswlvpadaleagdydritklareavegakl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2c0aC (C:)
amknwktsaesilttgpvvpvivvkklehavpmakalvaggvrvlnvtlrtecavdaira
iakevpeaivgagtvlnpqqlaevteagaqfaispgltepllkaategtiplipgistvs
elmlgmdyglkefkffpaeanggvkalqaiagpfsqvrfcptggispanyrdylalksvl
ciggswlvpadaleagdydritklareavegakl

    Sequence, based on observed residues (ATOM records): (download) 
    >2c0aC (C:)
mknwktsaesilttgpvvpvivvkklehavpmakalvaggvrvlnvtlrtecavdairai
akevpeaivgagtvlnpqqlaevteagaqfaispgltepllkaategtiplipgistvse
lmlgmdyglkefkffpaeanggvkalqaiagpfsqvrfcptggispanyrdylalksvlc
iggswlvpadaleagdydritklareavegakl