PDB entry 2c01

View 2c01 on RCSB PDB site
Description: crystal structures of eosinophil-derived neurotoxin in complex with the inhibitors 5'-ATP, ap3a, ap4a and ap5a
Class: hydrolase
Keywords: endonuclease, eosinophil, hydrolase, nuclease, ribonuclease, RNAse us, RNAse-2, inhibitor, 5'-ATP, ap3a, ap4a, ap5a, chemotaxis, glycoprotein, polymorphism, sensory transduction
Deposited on 2005-08-24, released 2006-01-18
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.24 Å
R-factor: 0.188
AEROSPACI score: 0.76 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'X':
    Compound: nonsecretory ribonuclease
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2C01 (0-0)
    • Uniprot P10153 (1-134)
    Domains in SCOPe 2.05: d2c01x_
  • Heterogens: ACY, ATP, HOH

PDB Chain Sequences:

  • Chain 'X':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2c01X (X:)
    mkppqftwaqwfetqhinmtsqqctnamqvinnyqrrcknqntfllttfanvvnvcgnpn
    mtcpsnktrknchhsgsqvplihcnlttpspqnisncryaqtpanmfyivacdnrdqrrd
    ppqypvvpvhldrii