PDB entry 2bzj

View 2bzj on RCSB PDB site
Description: crystal structure of the human pim1 in complex with a ruthenium organometallic ligand ru3
Class: transferase
Keywords: pim1, kinase, cancer, leukemia, nuclear protein, nucleotide-binding, transferase
Deposited on 2005-08-18, released 2005-10-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-08, with a file datestamp of 2019-05-03.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: proto-oncogene serine threonine protein kinase pim1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11309
      • engineered mutation (249)
    Domains in SCOPe 2.08: d2bzja_
  • Heterogens: ME3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2bzjA (A:)
mllskinslahlraapcndlhatklapgkekeplesqyqvgpllgsggfgsvysgirvsd
nlpvaikhvekdrisdwgelpngtrvpmevvllkkvssgfsgvirlldwferpdsfvlil
erpepvqdlfdfitergalqeelarsffwqvleavrhchncgvlhrdikdenilidlnrg
elklidfgsgallkdtvytdfdgtrvysppewiryhryhgrsaavwslgillydmvcgdi
pfehdeeiiggqvffrqrvssecqhlirwclalrpsdrptfeeiqnhpwmqdvllpqeta
eihlhslspgpsk

    Sequence, based on observed residues (ATOM records): (download) 
    >2bzjA (A:)
plesqyqvgpllgsggfgsvysgirvsdnlpvaikhvekdrisdwgelpngtrvpmevvl
lkkvssgfsgvirlldwferpdsfvlilerpepvqdlfdfitergalqeelarsffwqvl
eavrhchncgvlhrdikdenilidlnrgelklidfgsgallkdtvytdfdgtrvysppew
iryhryhgrsaavwslgillydmvcgdipfehdeeiiggqvffrqrvssecqhlirwcla
lrpsdrptfeeiqnhpwmqdvllpqetaeihlh